除抗氧化剂外的有机硒化合物。

IF 3.2 4区 医学 Q3 CHEMISTRY, MEDICINAL
Future medicinal chemistry Pub Date : 2024-12-01 Epub Date: 2024-12-22 DOI:10.1080/17568919.2024.2435254
Ritu Mamgain, Garima Mishra, Saumya Kriti, Fateh V Singh
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引用次数: 0

摘要

有机硒化学由于其在合成许多生物活性和治疗性化合物方面的作用而成为一个重要的领域。在早期阶段,研究人员专注于设计具有抗氧化性能的有机硒化合物,并取得了相当大的成功。在过去的二十年里,合成化学家将他们的重点转向合成具有生物特性的有机硒化合物,超越了传统的抗氧化特性。综述了有机硒化合物在抗癌、抗菌、抗病毒、降糖、抗甲状腺、抗炎等方面的合成和研究进展,以及在疾病治疗中的作用。本文综述了近10年来合成有机硒化合物的合成及其在医学上的应用,为药物化学领域的研究人员提供了宝贵的参考资料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Organoselenium compounds beyond antioxidants.

Organoselenium chemistry has become a significant field due to its role in synthesizing numerous biologically active and therapeutic compounds. In early phase, researchers focused on designing organoselenium compounds with antioxidant properties and were quite successful. In last two decades, synthetic chemists shifted their focus toward synthesis of organoselenium compounds with biological properties, moving beyond their traditional antioxidant properties. The review includes synthesis and study of organo-selenium compounds as anticancer, antimicrobial, antiviral, antidiabetic, antithyroid, anti-inflammatory therapies, contributing to disease treatment. This review covers the synthesis and medicinal applications of synthetic organoselenium compounds over the past 10 years, thus making it a valuable resource for researchers in the field of medicinal chemistry.

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来源期刊
Future medicinal chemistry
Future medicinal chemistry CHEMISTRY, MEDICINAL-
CiteScore
5.80
自引率
2.40%
发文量
118
审稿时长
4-8 weeks
期刊介绍: Future Medicinal Chemistry offers a forum for the rapid publication of original research and critical reviews of the latest milestones in the field. Strong emphasis is placed on ensuring that the journal stimulates awareness of issues that are anticipated to play an increasingly central role in influencing the future direction of pharmaceutical chemistry. Where relevant, contributions are also actively encouraged on areas as diverse as biotechnology, enzymology, green chemistry, genomics, immunology, materials science, neglected diseases and orphan drugs, pharmacogenomics, proteomics and toxicology.
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