Mathangi Kumar, Sulochana Badagabettu, Keerthilatha M Pai, Baby S Nayak
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This included 20 case reports and four case series which addressed various dental treatment procedures performed on people with mild/moderate/severe hemophilia A or hemophilia B. A total of 28 patients were presented with a mean age of 20.4 years. The pre-treatment factor ranged from 200 to 2500 IU and the post-treatment factor range was 1000-3000 IU.</p><p><strong>Conclusions: </strong>There was a wide range of variation in the utilization of prophylactic factors for dental treatment procedures among people with hemophilia. 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引用次数: 0
摘要
目的:分析血友病患者在牙科临床管理中所采用的各种牙科管理策略。方法:检索2000年1月至2023年8月期间,PubMed、Scopus、谷歌Scholar、Web of Science、EMBASE等数据库的病例报告和病例系列,采用MEDLINE电子数据库进行检索。病例报告涉及血友病A/血友病B患者的牙科治疗。排除获得性血友病病例和抑制剂阳性血友病病例。结果:共纳入286篇文献,其中24篇被纳入综述。这包括20例病例报告和4个病例系列,涉及对轻度/中度/重度血友病A或血友病b患者进行的各种牙科治疗程序。共有28例患者,平均年龄20.4岁。前处理因子为200 ~ 2500 IU,后处理因子为1000 ~ 3000 IU。结论:血友病患者在牙科治疗过程中预防因素的使用存在很大差异。这种差异强调需要更大规模的前瞻性临床研究,以解决使用凝血因子浓缩物的基本原理及其对轻度、中度或重度血友病患者牙科治疗结果的影响。
Dental management of people with congenital hemophilia: An integrative review of case reports and case series from a global scenario.
Objective: To analyze the various dental management strategies adopted to manage patients with hemophilia in a dental clinical setup.
Methods: An electronic database search was carried out using MEDLINE by PubMed, Scopus, Google Scholar, Web of Science, and EMBASE databases from January 2000 to August 2023 for case reports and case series published in English language. Case reports addressing the dental treatments for people with hemophilia A/hemophilia B were included. Cases of acquired hemophilia and cases of hemophilia who are inhibitor positive were excluded.
Results: There was a total of 286 articles that were identified of which 24 reports were included for the review. This included 20 case reports and four case series which addressed various dental treatment procedures performed on people with mild/moderate/severe hemophilia A or hemophilia B. A total of 28 patients were presented with a mean age of 20.4 years. The pre-treatment factor ranged from 200 to 2500 IU and the post-treatment factor range was 1000-3000 IU.
Conclusions: There was a wide range of variation in the utilization of prophylactic factors for dental treatment procedures among people with hemophilia. This variation highlights the need for larger prospective clinical studies that address the rationale for using clotting factor concentrate and its impact on dental treatment outcomes for individuals with mild, moderate, or severe hemophilia.
期刊介绍:
Special Care in Dentistry is the official journal of the Special Care Dentistry Association, the American Association of Hospital Dentists, the Academy of Dentistry for Persons with Disabilities, and the American Society for Geriatric Dentistry. It is the only journal published in North America devoted to improving oral health in people with special needs.