IF 1.9 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
Sudipta Saha
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引用次数: 0

摘要

姜黄(Curcuma longa)是一种多年生根状草本植物(姜科),含有姜黄素这种主要的药理活性植物化学物质,可以缓解许多严重的健康问题,如炎症、糖尿病、骨关节炎和类风湿性关节炎、癌症、肝胆疾病、腹泻、胃溃疡和消化性溃疡以及牛皮癣。它的起源可追溯到印度,但在中国、斯里兰卡、西非和东非等地区以及其他热带国家也有广泛种植。莪术在中国被称为 "姜黄 "或 "黄姜",在中国传统医学(中医)中发挥着重要的治疗作用。最近的研究还发现,莪术的生物活性物质具有神经保护活性、抗肥胖活性、心血管保护活性、抗氧化活性和抗菌活性。莪术中的各种生物活性植物化学物质是其生物活性的标志。在动物模型中对龙牙草进行的各种体外和体内研究证实了其多种植物化学成分的伦理医学活性。然而,对其波动前景的正确分析并没有应用到最新的创新疗法中。必须充分开发龙舌兰的各种生物活性植物化学成分的应用和作用机制。尽管如此,人体医学试验和质量控制研究对于确定龙舌兰及其主要植物化学物质姜黄素和其他具有药理活性的植物化学物质在治疗各种健康问题时的适量和无害程度至关重要。本综述将为制药业提供平台,以改进基于姜黄的制药材料。此外,姜黄基天然产品还具有安全、无毒、价格低廉、来源广泛等优点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Ethonomedical Profiles and Pharmacological Properties of Phytochemicals From Curcuma longa Linn. - A Decade Update

The rhizomatous herbaceous perennial plant (Zingiberaceae family) turmeric (Curcuma longa) contains curcumin as a major pharmacologically active phytochemical which can alleviate many serious health issues such as inflammation, diabetics, osteoarthritis and rheumatoid arthritis, cancer, hepatobiliary illness, diarrhea, gastric and peptic ulcers, and psoriasis. Its origins trace back to India, yet it's extensively grown in regions like China, Sri Lanka, West, and East Africa, as well as other tropical nations. Referred to as Jianghuang or Huangjiang in China, this plant plays a significant role in Chinese traditional medicine (TCM) for therapeutic purposes. Recent study also reported that Curcuma longa bioactive substances possess neuroprotective activity, antiobesity activity, cardio protective activity, antioxidant activities, and antimicrobial activities. The various bioactive phytochemicals present in C. longa is the hallmark of its bioactivity. Various in vitro and in vivo studies on C. longa in the animal model supports its ethonomedical activities of its numerous phytochemical constituents. Still the proper analysis of its fluctuating prospective is not applied into the emerging innovative treatments in finest situation. The full exploitation of the application and mechanism of action of various biologically active phytochemicals of C. longa has to be done. Although, human medical trials and quality control studies are essential to determine the adequate and innocuous quantity of C. longa and its key phytochemical curcumin along with other pharmacologically active phytochemicals for the management of various health issues. This review will offer platforms to the pharmaceutical industries to improve pharmaceutical materials based on turmeric. The added advantage is that the turmeric-based natural products are safe, nontoxic, inexpensive, and widely available.

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来源期刊
ChemistrySelect
ChemistrySelect Chemistry-General Chemistry
CiteScore
3.30
自引率
4.80%
发文量
1809
审稿时长
1.6 months
期刊介绍: ChemistrySelect is the latest journal from ChemPubSoc Europe and Wiley-VCH. It offers researchers a quality society-owned journal in which to publish their work in all areas of chemistry. Manuscripts are evaluated by active researchers to ensure they add meaningfully to the scientific literature, and those accepted are processed quickly to ensure rapid online publication.
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