IF 3.5 3区 医学 Q2 NUTRITION & DIETETICS
Ashlea Hambleton, Daniel Le Grange, Marcellinus Kim, Jane Miskovic-Wheatley, Stephen Touyz, Sarah Maguire
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引用次数: 0

摘要

背景:由于训练有素的员工队伍有限、员工流动性大以及治疗效果不稳定,对于生活在农村或地区的厌食症青少年来说,很难获得循证治疗,如家庭治疗(FBT)。远程医疗为患者提供了一种潜在的就医解决方案,无论其家庭或服务地点在哪里,都可以方便地接受治疗。COVID-19 对医疗系统造成的破坏扩大了现有的需求,在对其有效性和安全性进行全面评估之前,远程医疗在提供 FBT 方面的使用增加了。本研究旨在评估远程医疗-FBT 的可行性、可接受性和初步疗效,该疗法由农村服务机构中的社区临床医生直接在家中提供,以减轻被诊断为 AN 的青少年的饮食失调症状:方法:通过实施前和实施后的多地点病例系列,为居住在澳大利亚农村或地区的 28 名青少年(89.29% 为女性,M = 14.68 ± 1.58 岁)提供多达 20 次的远程保健-FBT 治疗。评估以RE-AIM框架为指导,通过Reach(治疗接受和完成)、Efficacy(体重变化、整体饮食失调症状以及从基线到治疗结束和6个月随访期间的缓解)、Adoption(患者特征和辍学)、Implementation(干预忠实性)和Maintenance(随访期间的结果和干预)来评估远程保健-FBT的可行性和初步疗效:结果:人们对远程保健-FBT 的兴趣很高,三分之二符合条件的家庭同意参与。治疗参与率和完成率都超过了 60%,治疗的忠实度也可以接受。20名青少年(71.43%)符合自闭症的诊断标准(基线为86.03%mBMI ± 7.14),8名青少年(28.57%)符合非典型自闭症的诊断标准(基线为101.34%mBMI ± 8.28),总体平均病程为8.53个月(SD = 5.39,范围为2-24个月)。与基线相比,治疗结束时的体重指数(%mBMI)明显增加(p = 0.007,95%CI:1.04-6.65),超过68%的青少年体重得到恢复,其中36.8%的青少年同时达到了体重和心理缓解标准。在六个月的随访中,体重仍有明显改善(p = 0.005,95%CI:1.57-8.65)。此外,在治疗结束时,由家长评定的青少年总体饮食失调症状与基线相比下降了 0.735(p = 0.028,95%CI:0.079-1.385):结论:远程保健-FBT 在农村服务中的实施是可行的,由社区临床医生提供,其覆盖范围、采用率、初步疗效和忠实度评分与专家研究报告的评分相当:该研究按照HREC批准的方案(HREC 2020/ETH00186)进行,并在澳大利亚和新西兰临床试验注册中心(ANZCTR # 12620001107910)注册。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Delivering evidence-based treatment via telehealth for Anorexia Nervosa in rural health settings: a multi-site feasibility implementation study.

Background: Access to evidence-based treatments such as family-based therapy (FBT) is difficult for adolescents diagnosed with Anorexia Nervosa (AN) living in rural or regional areas due to a limited trained workforce, high staff turnover and inconsistent treatment fidelity. Telehealth offers a potential access solution by facilitating care irrespective of family or service location. The disruption to the health system caused by COVID-19 amplified an existing need and increased the use of telehealth to deliver FBT before its efficacy and safety was fully evaluated. This study aimed to evaluate the feasibility, acceptability and preliminary efficacy of telehealth-FBT delivered by community-based clinicians within rural services directly into the home to reduce the eating disorder symptoms of adolescents diagnosed with AN.

Methods: A pre- and post-implementation multi-site case series delivered up to 20 sessions of telehealth-FBT to 28 adolescents (89.29% female, M = 14.68 ± 1.58 years) living in rural or regional Australia. The RE-AIM framework guided the evaluation, with Reach (treatment uptake and completion); Efficacy (change in weight, global eating disorder symptoms, and remission from baseline to end of treatment and six-month follow-up); Adoption (patient characteristics and drop out); Implementation (intervention fidelity) and Maintenance (outcomes and intervention during the follow-up period) used to assess the feasibility and preliminary efficacy of telehealth-FBT.

Results: There was a high level of interest in telehealth-FBT, with two-thirds of eligible families consenting to participate. Both treatment engagement and completion rates were over 60%, and treatment was delivered with acceptable fidelity. Twenty adolescents (71.43%) met the diagnostic criteria for AN (baseline 86.03%mBMI ± 7.14), and eight (28.57%) for Atypical AN (baseline 101.34%mBMI ± 8.28), with an overall mean duration of illness of 8.53 months (SD = 5.39, range 2-24 months). There was a significant increase in %mBMI at the end of treatment compared to the baseline (p = 0.007, 95%CI: 1.04-6.65), with over 68% of adolescents weight restored and 36.8% of these achieving both weight and psychological remission criteria. Weight remained significantly improved at six-month follow-up (p = 0.005, 95%CI: 1.57-8.65). Also, there was a decrease in adolescents' global eating disorder symptoms, as rated by their parents, at the end of treatment compared to the baseline of 0.735 (p = 0.028, 95%CI: 0.079-1.385).

Conclusions: Telehealth-FBT was feasibly implemented into rural services and delivered by community clinicians with reach, adoption, preliminary efficacy, and fidelity scores comparable to those reported by specialist studies.

Trial registration: The study was conducted according to the HREC-approved protocol (HREC 2020/ETH00186) and registered with the Australian and New Zealand Clinical Trials Registry (ANZCTR # 12620001107910).

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来源期刊
Journal of Eating Disorders
Journal of Eating Disorders Neuroscience-Behavioral Neuroscience
CiteScore
5.30
自引率
17.10%
发文量
161
审稿时长
16 weeks
期刊介绍: Journal of Eating Disorders is the first open access, peer-reviewed journal publishing leading research in the science and clinical practice of eating disorders. It disseminates research that provides answers to the important issues and key challenges in the field of eating disorders and to facilitate translation of evidence into practice. The journal publishes research on all aspects of eating disorders namely their epidemiology, nature, determinants, neurobiology, prevention, treatment and outcomes. The scope includes, but is not limited to anorexia nervosa, bulimia nervosa, binge eating disorder and other eating disorders. Related areas such as important co-morbidities, obesity, body image, appetite, food and eating are also included. Articles about research methodology and assessment are welcomed where they advance the field of eating disorders.
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