Silvia Valeggia, Marjolein H G Dremmen, Irene M J Mathijssen, Linda Gaillard, Renzo Manara, Riccardo Ceccato, Martijn van Hattem, Renske Gahrmann
{"title":"黑骨核磁共振成像与 CT 在颅骨发育不良症颞骨评估中的对比:无辐射替代方案。","authors":"Silvia Valeggia, Marjolein H G Dremmen, Irene M J Mathijssen, Linda Gaillard, Renzo Manara, Riccardo Ceccato, Martijn van Hattem, Renske Gahrmann","doi":"10.1007/s00234-024-03525-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and purpose: </strong>Craniosynostoses are rare congenital craniofacial malformations, variably affected by hearing loss, often requiring repeated CT examinations to assess skull or temporal bone (TB) abnormalities. In order to avoid radiation exposure in these young patients, efforts are made to assess the skull abnormalities on MR bone imaging sequences, such as Black Bone (BB). Our aim is to compare BB, a radiation-free imaging technique, with CT for the assessment of the TB.</p><p><strong>Materials and methods: </strong>48 patients who underwent both BB and CT (2016-2021) in Sophia Children's Hospital, Erasmus MC, Rotterdam, were retrospectively investigated. BB and CT (the diagnostic gold standard for imaging the temporal bone) were evaluated blindly and independently by 3 observers; visibility and abnormalities of TB structures and cranial nerves were scored; abnormal findings were confirmed by a senior pediatric neuroradiologist. The statistical analysis was performed using Gwet's AC1 agreement and modified versions of the Wilcoxon signed-rank test and sign test with a Bonferroni-Holm correction (p < 0.05).</p><p><strong>Results: </strong>CT was rated higher than BB in structure visibility (global p = 0.0002), but was rated similar to BB when assessing TB anatomy and pathology (global p = 0.58). The visibility ratings showed better interobserver agreement values on CT than BB. In the normal/abnormal ratings, both BB (0.75-1) and CT (0.88-1) showed high interobserver agreement values.</p><p><strong>Conclusion: </strong>Our preliminary results suggest that BB is a promising tool for screening TB pathology in patients with craniosynostosis who require MR imaging.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Black Bone MRI vs. CT in temporal bone assessment in craniosynostosis: a radiation-free alternative.\",\"authors\":\"Silvia Valeggia, Marjolein H G Dremmen, Irene M J Mathijssen, Linda Gaillard, Renzo Manara, Riccardo Ceccato, Martijn van Hattem, Renske Gahrmann\",\"doi\":\"10.1007/s00234-024-03525-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and purpose: </strong>Craniosynostoses are rare congenital craniofacial malformations, variably affected by hearing loss, often requiring repeated CT examinations to assess skull or temporal bone (TB) abnormalities. In order to avoid radiation exposure in these young patients, efforts are made to assess the skull abnormalities on MR bone imaging sequences, such as Black Bone (BB). Our aim is to compare BB, a radiation-free imaging technique, with CT for the assessment of the TB.</p><p><strong>Materials and methods: </strong>48 patients who underwent both BB and CT (2016-2021) in Sophia Children's Hospital, Erasmus MC, Rotterdam, were retrospectively investigated. BB and CT (the diagnostic gold standard for imaging the temporal bone) were evaluated blindly and independently by 3 observers; visibility and abnormalities of TB structures and cranial nerves were scored; abnormal findings were confirmed by a senior pediatric neuroradiologist. The statistical analysis was performed using Gwet's AC1 agreement and modified versions of the Wilcoxon signed-rank test and sign test with a Bonferroni-Holm correction (p < 0.05).</p><p><strong>Results: </strong>CT was rated higher than BB in structure visibility (global p = 0.0002), but was rated similar to BB when assessing TB anatomy and pathology (global p = 0.58). The visibility ratings showed better interobserver agreement values on CT than BB. In the normal/abnormal ratings, both BB (0.75-1) and CT (0.88-1) showed high interobserver agreement values.</p><p><strong>Conclusion: </strong>Our preliminary results suggest that BB is a promising tool for screening TB pathology in patients with craniosynostosis who require MR imaging.</p>\",\"PeriodicalId\":19422,\"journal\":{\"name\":\"Neuroradiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuroradiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00234-024-03525-6\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroradiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00234-024-03525-6","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Black Bone MRI vs. CT in temporal bone assessment in craniosynostosis: a radiation-free alternative.
Background and purpose: Craniosynostoses are rare congenital craniofacial malformations, variably affected by hearing loss, often requiring repeated CT examinations to assess skull or temporal bone (TB) abnormalities. In order to avoid radiation exposure in these young patients, efforts are made to assess the skull abnormalities on MR bone imaging sequences, such as Black Bone (BB). Our aim is to compare BB, a radiation-free imaging technique, with CT for the assessment of the TB.
Materials and methods: 48 patients who underwent both BB and CT (2016-2021) in Sophia Children's Hospital, Erasmus MC, Rotterdam, were retrospectively investigated. BB and CT (the diagnostic gold standard for imaging the temporal bone) were evaluated blindly and independently by 3 observers; visibility and abnormalities of TB structures and cranial nerves were scored; abnormal findings were confirmed by a senior pediatric neuroradiologist. The statistical analysis was performed using Gwet's AC1 agreement and modified versions of the Wilcoxon signed-rank test and sign test with a Bonferroni-Holm correction (p < 0.05).
Results: CT was rated higher than BB in structure visibility (global p = 0.0002), but was rated similar to BB when assessing TB anatomy and pathology (global p = 0.58). The visibility ratings showed better interobserver agreement values on CT than BB. In the normal/abnormal ratings, both BB (0.75-1) and CT (0.88-1) showed high interobserver agreement values.
Conclusion: Our preliminary results suggest that BB is a promising tool for screening TB pathology in patients with craniosynostosis who require MR imaging.
期刊介绍:
Neuroradiology aims to provide state-of-the-art medical and scientific information in the fields of Neuroradiology, Neurosciences, Neurology, Psychiatry, Neurosurgery, and related medical specialities. Neuroradiology as the official Journal of the European Society of Neuroradiology receives submissions from all parts of the world and publishes peer-reviewed original research, comprehensive reviews, educational papers, opinion papers, and short reports on exceptional clinical observations and new technical developments in the field of Neuroimaging and Neurointervention. The journal has subsections for Diagnostic and Interventional Neuroradiology, Advanced Neuroimaging, Paediatric Neuroradiology, Head-Neck-ENT Radiology, Spine Neuroradiology, and for submissions from Japan. Neuroradiology aims to provide new knowledge about and insights into the function and pathology of the human nervous system that may help to better diagnose and treat nervous system diseases. Neuroradiology is a member of the Committee on Publication Ethics (COPE) and follows the COPE core practices. Neuroradiology prefers articles that are free of bias, self-critical regarding limitations, transparent and clear in describing study participants, methods, and statistics, and short in presenting results. Before peer-review all submissions are automatically checked by iThenticate to assess for potential overlap in prior publication.