A型流感病毒引起的急性呼吸窘迫综合征患者血小板分布宽度：一个具有临床应用前景的老指标

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-12-15 DOI:10.1016/j.diagmicrobio.2024.116657

Xiang Fang , Jinhui Gao , Ziyi Zhang , Xuanzhe Yang , Qin Wang , Jiajia Wang

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引用次数: 0

摘要

本研究旨在探讨血小板分布宽度（PDW）在甲型流感病毒（IAV）感染患者中的预测价值。收集并分析了105例iav感染患者的临床资料。我们发现肌酸激酶（CK）、急性生理和慢性健康评估（APACHE） II评分、PDW和红细胞分布宽度（RDW）是急性呼吸窘迫综合征（ARDS）发展的独立危险因素。PDW比CK和RDW更有效地预测ARDS的发展，与APACHE II评分相当。在ARDS患者中，PDW与有创通气时间、APACHEⅱ评分、序贯器官衰竭评分（SOFA）呈正相关，与动脉血氧压/吸气氧分数（PaO2/FiO2）水平呈负相关。此外，PDW对感染性休克和28天死亡率具有较高的预测效率。综上所述，本研究表明PDW在ivv诱导的ARDS患者中具有良好的临床价值。

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Platelet distribution width in patients with influenza A virus-induced acute respiratory distress syndrome: An old indicator with promising clinical application

This study aims to investigate the predictive value of platelet distribution width (PDW) in patients with influenza A virus (IAV) infection. The clinical data of 105 IAV-infected patients was collected and analyzed. We found that creatine kinase (CK), Acute Physiology and Chronic Health Evaluation (APACHE) II score, PDW, and red blood cell distribution width (RDW) were independent risk factors for acute respiratory distress syndrome (ARDS) development. PDW was more effective in predicting ARDS development than CK and RDW, and comparable to APACHE II score. Among ARDS patients, PDW showed a positive correlation with duration of invasive ventilation, APACHE II score, and Sequential Organ Failure Assessment (SOFA) score, and a negative correlation with the arterial pressure of oxygen/inspiratory fraction of oxygen (PaO₂/FiO₂) level. Furthermore, PDW showed high predictive efficiency for septic shock and 28-day mortality. Taken together, this study demonstrated a promising clinical value of PDW in patients with IAV-induced ARDS.

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.