电纺三维纳米纤维材料及其在骨科中的应用

IF 23.2 2区 材料科学 Q1 MATERIALS SCIENCE, COMPOSITES
Yuanhe Wang, Nana Shen, Zhongze Zhu, Jiarui Liu, Xiaoying Qi, Zhong Liu, Youfu Zhu, Xiaoxiong Wang, Yunze Long, Hongfei Xiang
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引用次数: 0

摘要

先进的现代技术将生物医学和材料科学推向了科学研究的前沿。随着现代科学的发展,各学科之间需要更大的协同作用。在骨科领域,复杂的骨结构需要植入物来平衡强度和孔隙度。这一双重要求呼唤着跨越生物医学和材料科学领域的深刻把握,敦促深入研究这两个领域,以制造出完美的骨植入材料协同作用。本文从材料学和骨科科学的角度出发,系统地讨论了静电纺丝技术制备用于骨科的三维多孔结构材料。它首先详细介绍了静电纺丝技术,它们的原理,过程,材料和材料科学中的设计策略。然后介绍了材料表征方法。在生物医学方面,我们提供了从细胞活力到染色的标准测试方法的简明概述。基于这两个领域的基础知识,综述了三维静电纺丝技术,并总结了近年来该技术在骨组织培养方面的研究进展。本综述旨在为研究人员提供交叉学科的结构化理解,为根据骨科特定需求量身定制的材料创新奠定坚实的基础。图形抽象
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Electrospun 3D nanofibrous materials and their applications in orthopaedics

Advancing modern technology has propelled biomedicine and materials science to the forefront of scientific interest. As modern science evolves, it demands greater synergy between disciplines. In the realm of orthopaedics, the complex architecture of bone necessitates implants that balance strength with porosity. This dual requirement beckons a profound grasp that spans the realms of biomedicine and materials science, urging a deep dive into both fields to craft the perfect synergy for bone implant materials. Journeying through materials and orthopaedic science, this article systematically discussed the preparation of 3D porous structures by electrospinning technology for orthopaedics. It began by detailing electrospinning techniques, their principles, processes, materials, and design strategies within materials science. Material characterization methods were then presented. In biomedicine, we offered a concise overview of standard testing methods, from cell viability to staining. Building on the foundational knowledge of both fields, it reviewed 3D electrospinning strategies and summarized recent research progress in bone tissue culture with this method. This review sought to offer a structured comprehension of the intersecting disciplines to researchers, establishing a robust basis for material innovation tailored to orthopaedic-specific demands.

Graphical abstract

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来源期刊
CiteScore
26.00
自引率
21.40%
发文量
185
期刊介绍: Advanced Composites and Hybrid Materials is a leading international journal that promotes interdisciplinary collaboration among materials scientists, engineers, chemists, biologists, and physicists working on composites, including nanocomposites. Our aim is to facilitate rapid scientific communication in this field. The journal publishes high-quality research on various aspects of composite materials, including materials design, surface and interface science/engineering, manufacturing, structure control, property design, device fabrication, and other applications. We also welcome simulation and modeling studies that are relevant to composites. Additionally, papers focusing on the relationship between fillers and the matrix are of particular interest. Our scope includes polymer, metal, and ceramic matrices, with a special emphasis on reviews and meta-analyses related to materials selection. We cover a wide range of topics, including transport properties, strategies for controlling interfaces and composition distribution, bottom-up assembly of nanocomposites, highly porous and high-density composites, electronic structure design, materials synergisms, and thermoelectric materials. Advanced Composites and Hybrid Materials follows a rigorous single-blind peer-review process to ensure the quality and integrity of the published work.
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