点评：迈向最佳避孕剂量策略。

IF 3.8 2区生物学 Q1 BIOCHEMICAL RESEARCH METHODS

PLoS Computational Biology Pub Date : 2024-12-18 eCollection Date: 2024-12-01 DOI:10.1371/journal.pcbi.1012398

Giuseppe Benagiano, Andrea R Genazzani, Giovanni Grandi, Sun-Wei Guo, Marwan Habiba

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引用次数: 0

摘要

Gavina等人最近提出的最佳避孕剂量策略是一个值得称赞的尝试，它模拟了一个复杂的生理过程，有可能应用于现实生活数据。然而，有必要考虑到从理论到实际应用过程中出现的真正挑战，并且在任何理论建模中考虑临床研究的经验教训是很重要的。在本文中，我们详细阐述了这些经验教训，并阐述了其模式面临的实际挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Comment on: Toward an optimal contraception dosing strategy.

The optimal contraception dosing strategy proposed by Gavina et al. recently is a commendable attempt to model a complex physiological process with potenial to apply to real-life data. However, there is a need to take into account the real challenges that arise when moving from the theory to its practical application, and it is important that lessons learnt from clinical studies be taken into consideration in any theoretical modelling. In this manuscript, we spell out these lessons and elaborate practical challenges facing their model.

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来源期刊

PLoS Computational Biology BIOCHEMICAL RESEARCH METHODS-MATHEMATICAL & COMPUTATIONAL BIOLOGY

CiteScore

7.10

自引率

4.70%

发文量

820

审稿时长

2.5 months

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