- Book学术

发布求助

文献互助智能选刊最新文献

IF 2.5 4区医学 Q3 BUSINESS

Nutricion hospitalaria Pub Date : 2024-12-13 DOI:10.20960/nh.05517

Qianran Kong, Lijuan Tian, Yihan Wang, Min Yu

{"title":"Phase angle as a prognostic factor in patients with cancer: a systematic review of the existing evidence via a meta-analysis.","authors":"Qianran Kong, Lijuan Tian, Yihan Wang, Min Yu","doi":"10.20960/nh.05517","DOIUrl":null,"url":null,"abstract":"Background: the phase angle (PA) is expressed via bioelectrical impedance and an indicator of cell membrane health, integrity, hydration, and nutritional status. The associations between PA and cancer survival are inconsistent and unclear. This study aimed to assess PA's role as a prognostic marker of cancer survival.Methods: we searched PubMed and EMBASE to identify all relevant studies up to December 2023. A meta-analysis was performed to clarify PA's prognostic role for cancer patients.Results: a total of 30 studies covering 6587 participants were included in this study. There was a significant prognostic role for PA in the context of cancer patients' survival (HR = 0.73; 95 % CI, 0.66-0.81, p < 0.0001, I2 = 0.0 %). Patients with low PA values were 27 % less likely to survive than patients with high values. Our subgroup analyses showed that geographical population (American: HR = 0.66, 95 % CI: 0.55-0.79, I2 = 0.0 %; European: HR = 0.63, 95 % CI: 0.47-0.84, I2 = 23.2 %; Asian: HR = 0.48, 95 % CI: 0.31-0.74), the type of cancer (head and neck, colorectal, lung, or pancreatic cancer), and type of therapy (palliative vs. non-palliative treatment) did not change the prognostic value.Conclusions: the findings highlight the potential of PA to be a non-invasive, cost-effective prognostic tool in oncological care.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutricion hospitalaria","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.20960/nh.05517","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BUSINESS","Score":null,"Total":0}

引用次数: 0

摘要

背景：相位角（PA）通过生物电阻抗表示，是细胞膜健康、完整性、水合和营养状况的指标。PA 与癌症存活率之间的关联并不一致，也不清楚。本研究旨在评估 PA 作为癌症生存预后指标的作用。方法：我们检索了 PubMed 和 EMBASE，以确定截至 2023 年 12 月的所有相关研究。结果：本研究共纳入了 30 项研究，涉及 6587 名参与者。PA对癌症患者的生存有明显的预后作用（HR = 0.73; 95 % CI, 0.66-0.81, p < 0.0001, I2 = 0.0 %）。PA值低的患者存活率比PA值高的患者低27%。我们的亚组分析表明，地域人群（美国人、加拿大人、澳大利亚人和新西兰人）的PA值越低，存活率越高：HR=0.66，95% CI：0.55-0.79，I2=0.0%；欧洲人：HR=0.63，95% CI：0.47-0.84，I2=23.2%；亚洲人：HR=0.48，95% CI：0.31-0.74）、癌症类型（头颈癌、结直肠癌、肺癌或胰腺癌）和治疗类型（姑息治疗与非姑息治疗）均无变化。结论：研究结果凸显了 PA 在肿瘤治疗中作为一种无创、经济有效的预后工具的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Phase angle as a prognostic factor in patients with cancer: a systematic review of the existing evidence via a meta-analysis.

Background: the phase angle (PA) is expressed via bioelectrical impedance and an indicator of cell membrane health, integrity, hydration, and nutritional status. The associations between PA and cancer survival are inconsistent and unclear. This study aimed to assess PA's role as a prognostic marker of cancer survival.

Methods: we searched PubMed and EMBASE to identify all relevant studies up to December 2023. A meta-analysis was performed to clarify PA's prognostic role for cancer patients.

Results: a total of 30 studies covering 6587 participants were included in this study. There was a significant prognostic role for PA in the context of cancer patients' survival (HR = 0.73; 95 % CI, 0.66-0.81, p < 0.0001, I2 = 0.0 %). Patients with low PA values were 27 % less likely to survive than patients with high values. Our subgroup analyses showed that geographical population (American: HR = 0.66, 95 % CI: 0.55-0.79, I2 = 0.0 %; European: HR = 0.63, 95 % CI: 0.47-0.84, I2 = 23.2 %; Asian: HR = 0.48, 95 % CI: 0.31-0.74), the type of cancer (head and neck, colorectal, lung, or pancreatic cancer), and type of therapy (palliative vs. non-palliative treatment) did not change the prognostic value.

Conclusions: the findings highlight the potential of PA to be a non-invasive, cost-effective prognostic tool in oncological care.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nutricion hospitalaria 医学-营养学

CiteScore

1.90

自引率

8.30%

发文量

181

审稿时长

3-6 weeks

期刊介绍： The journal Nutrición Hospitalaria was born following the SENPE Bulletin (1981-1983) and the SENPE journal (1984-1985). It is the official organ of expression of the Spanish Society of Clinical Nutrition and Metabolism. Throughout its 36 years of existence has been adapting to the rhythms and demands set by the scientific community and the trends of the editorial processes, being its most recent milestone the achievement of Impact Factor (JCR) in 2009. Its content covers the fields of the sciences of nutrition, with special emphasis on nutritional support.