血细胞计数比预测挤压综合征患者不良结局的预后准确性。

IF 3.9 2区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Taner Karlidag, Olgun Bingol, Baran Sarikaya, Omer Halit Keskin, Atahan Durgal, Guzelali Ozdemir
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引用次数: 0

摘要

这项研究的基本原理是缺乏一个准确的预测指标来促进挤压综合征的治疗管理和预测预后。我们的研究旨在探讨以下问题:(1) 入院时的血细胞计数比值与挤压综合征的不良预后之间是否存在相关性? (2) 如果存在相关性,那么预测这些不良预后的血细胞计数比值的精确阈值是多少?在这项单中心、回顾性设计的研究中,我们分析了卡赫拉曼马拉大地震后入住本院的所有患者。重症监护室的住院时间和死亡率数据均通过医院系统获得。入院时计算并记录了血细胞计数比率。截肢患者、接受重症监护室(ICU)治疗的患者和死亡患者入院时的 NLR 值明显较高。(NLR值大于109.844,截肢风险增加8.188倍;CLR值大于64.518,需要入住重症监护室的可能性增加10.117倍;CLR值大于116.00,死亡风险增加5.519倍。NLR、MLR、NAR 和 CLR 等血细胞计数比率在预测挤压综合征患者的不良预后和死亡率方面具有合理的准确性。因此,为了今后更好地进行灾难管理,在入院时测定这些数值应作为预测挤压综合征患者预后的辅助工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prognostic accuracy of blood cell count ratios in predicting adverse outcomes in crush syndrome patients.

Prognostic accuracy of blood cell count ratios in predicting adverse outcomes in crush syndrome patients.

Prognostic accuracy of blood cell count ratios in predicting adverse outcomes in crush syndrome patients.

Prognostic accuracy of blood cell count ratios in predicting adverse outcomes in crush syndrome patients.

The rationale behind this study was the lack of an accurate predictor to facilitate treatment management and anticipate prognosis in crush syndrome. Our research aimed to investigate the following: (1) Is there a correlation between the ratios of blood cell counts upon admission and the adverse outcomes of crush syndrome? and (2) if such a correlation exists, what are the precise thresholds of blood cell count ratios for predicting these adverse outcomes? In this single-centered and retrospective design study, we analyzed all patients admitted to our hospital after Kahramanmaras Earthquake. The data on length of stay in the ICU and mortality status were obtained using our hospital system. Ratios of blood cell count were calculated and recorded at the time of admission. The NLR values in admission were significantly higher in patients with amputation, patients who received intensive care unit (ICU), and patients who died. (p < 0.001, p < 0.001 and p = 0.001, respectively). The MLR values were significantly increased in patients who underwent amputation and patients who received ICU (p < 0.001 and p = 0.003, respectively). NAR values in admission were significantly higher in patients with amputation, patients who received intensive care unit (ICU), and patients who died (p < 0.001, p < 0.001, and p = 0.002, respectively). In addition, according to binary logistic regression analysis, with a CLR value of > 109.844, the risk of amputation increases 8.188 fold; with a CLR value of > 64.518, the possibility of ICU admission requirement increases 10.117 fold, and with a CLR value of > 116.00, the risk of death increases 5.519 fold. Ratios of blood cell count such as NLR, MLR, NAR, and CLR offer a reasonable prognostic accuracy in predicting adverse outcomes and mortality in patients with crush syndrome. Therefore, for better disaster management in the future, the determination of these values at admission should be used as an adjunct tool for predicting prognosis in patients with crush syndrome.

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来源期刊
Scientific Reports
Scientific Reports Natural Science Disciplines-
CiteScore
7.50
自引率
4.30%
发文量
19567
审稿时长
3.9 months
期刊介绍: We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections. Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021). •Engineering Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live. •Physical sciences Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics. •Earth and environmental sciences Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems. •Biological sciences Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. •Health sciences The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
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