[天津市男男性行为者人类乳头瘤病毒感染状况及相关因素分析]。

Q1 Medicine

中华流行病学杂志 Pub Date : 2024-12-10 DOI:10.3760/cma.j.cn112338-20240617-00355

H J Li, J Y Bai, M H Yu, X Y Dong, T L Ning, J J Zhu, Y Zhang

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Results: The infection rate of HPV was 53.67% (322/600) in MSM, with high-risk type as 41.17% (247/600), low-risk type as 27.17% (163/600). The infection rate of HPV in both multiple and single types was 26.83% (161/600).The infection rates of genotypes covered by nine-valent HPV vaccine, quadrivalent HPV vaccine and bivalent HPV vaccine were 36.83% (221/600), 25.17% (151/600) and 9.50% (57/600), respectively.The infection rates of genital HPV, high-risk or low-risk types were 24.67% (148/600), 16.67% (100/600) and 11.00% (66/600), respectively. The infection rates of perianal HPV, high-risk or low-risk types were 42.00% (252/600), 30.17% (181/600) and 20.50% (123/600), respectively. The infection rates of oral HPV high-risk and low-risk types were 3.17% (19/600), 2.33% (14/600) and 1.17% (7/600), respectively. 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引用次数: 0

摘要

目的：分析天津市男男性行为者（MSM）多部位人乳头瘤病毒（HPV）感染现状及相关因素。方法：采用横断面调查方法，于2023年9 - 12月在天津市招募600名男男性行为者，按年龄分层，其中18-26岁200人、27-45岁300人、≥46岁100人。采用问卷调查的方式收集与人口统计学、性病防治相关的知识和行为信息。收集生殖器、肛周和口腔脱落细胞进行HPV分型检测。采用Logistic回归模型分析HPV感染的相关因素。结果：MSM人群HPV感染率为53.67%(322/600)，高危型为41.17%(247/600)，低危型为27.17%（163/600）。HPV多型和单型感染率均为26.83%（161/600）。九价HPV疫苗、四价HPV疫苗和二价HPV疫苗覆盖的基因型感染率分别为36.83%（221/600）、25.17%（151/600）和9.50%（57/600）。生殖器HPV、高危型和低危型的感染率分别为24.67%（148/600）、16.67%（100/600）和11.00%（66/600）。肛周HPV、高危型和低危型感染率分别为42.00%（252/600）、30.17%（181/600）和20.50%（123/600）。口腔HPV高危型和低危型感染率分别为3.17%（19/600）、2.33%（14/600）和1.17%（7/600）。离婚或丧偶（aOR=2.38, 95%CI: 1.26 ~ 4.50）、近6个月内有同性肛交史（aOR=2.28, 95%CI: 1.00 ~ 5.50）、依赖药物（包括新型精神活性物质）使用（aOR=1.62, 95%CI: 1.02 ~ 2.58）是生殖器HPV感染的危险因素。大专以上学历（aOR=0.36, 95%CI: 0.16 ~ 0.81）是肛周HPV感染的保护因素，药物依赖史（aOR=1.85, 95%CI: 1.19 ~ 2.88）是危险因素。结论：天津市MSM人群是HPV感染的高危人群，肛周区HPV感染较生殖器区和口腔区严重。婚姻状况、文化程度、近6个月同性肛交史、药物依赖史是MSM人群HPV感染的相关因素。

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[Analysis of human papillomavirus infection status and related factors among men who have sex with men in Tianjin].

Objective: The status quo and related factors of human papillomavirus (HPV) infection in multiple parts of men who have sex with men (MSM) in Tianjin were analyzed. Methods: Using the cross-sectional survey method, a total of 600 MSM were recruited in Tianjin from September to December 2023, including 200 (18-26 years old), 300 (27-45 years old), and 100 (≥46 years old) stratificaed by age group. Questionnaire survey was used to collect knowledge and behavioral information related to demography and STD prevention and treatment. Exfoliated cells from genital, perianal and oral cavity were collected for HPV typing detection. Logistic regression model was used to analyze the related factors of HPV infection. Results: The infection rate of HPV was 53.67% (322/600) in MSM, with high-risk type as 41.17% (247/600), low-risk type as 27.17% (163/600). The infection rate of HPV in both multiple and single types was 26.83% (161/600).The infection rates of genotypes covered by nine-valent HPV vaccine, quadrivalent HPV vaccine and bivalent HPV vaccine were 36.83% (221/600), 25.17% (151/600) and 9.50% (57/600), respectively.The infection rates of genital HPV, high-risk or low-risk types were 24.67% (148/600), 16.67% (100/600) and 11.00% (66/600), respectively. The infection rates of perianal HPV, high-risk or low-risk types were 42.00% (252/600), 30.17% (181/600) and 20.50% (123/600), respectively. The infection rates of oral HPV high-risk and low-risk types were 3.17% (19/600), 2.33% (14/600) and 1.17% (7/600), respectively. Divorce or widowhood (aOR=2.38, 95%CI: 1.26-4.50), history of homosexual anal intercourse in the past 6 months (aOR=2.28, 95%CI: 1.00-5.50), and use of dependent drugs (including new psychoactive substances) (aOR=1.62, 95%CI: 1.02-2.58) were risk factors for genital HPV infection. College degree/university degree or above (aOR=0.36, 95%CI: 0.16-0.81) was a protective factor for perianal HPV infection, and a history of drug dependence (aOR=1.85, 95%CI: 1.19-2.88) was a risk factor. Conclusions: MSM in Tianjin was a high-risk group for HPV infection, and the HPV infection in the perianal area was more severe than in the genital area and oral area.Marital status, education level, history of homosexual anal sex in the past 6 months, and history of drug dependence were related factors of HPV infection among MSM.

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来源期刊

中华流行病学杂志 Medicine-Medicine (all)

CiteScore

5.60

自引率

0.00%

发文量

8981

期刊介绍： Chinese Journal of Epidemiology, established in 1981, is an advanced academic periodical in epidemiology and related disciplines in China, which, according to the principle of integrating theory with practice, mainly reports the major progress in epidemiological research. The columns of the journal include commentary, expert forum, original article, field investigation, disease surveillance, laboratory research, clinical epidemiology, basic theory or method and review, etc. The journal is included by more than ten major biomedical databases and index systems worldwide, such as been indexed in Scopus, PubMed/MEDLINE, PubMed Central (PMC), Europe PubMed Central, Embase, Chemical Abstract, Chinese Science and Technology Paper and Citation Database (CSTPCD), Chinese core journal essentials overview, Chinese Science Citation Database (CSCD) core database, Chinese Biological Medical Disc (CBMdisc), and Chinese Medical Citation Index (CMCI), etc. It is one of the core academic journals and carefully selected core journals in preventive and basic medicine in China.