体外受精与儿童神经认知发育关系的研究进展。

IF 3.2 3区 医学 Q2 GENETICS & HEREDITY
Nicholas Aderinto, Emmanuel Kokori, Gbolahan Olatunji, Ikponmwosa Jude Ogieuhi, Israel Charles Abraham, Bonaventure Michael Ukoaka, Adetola Emmanuel Babalola, Yewande Abigail Adebayo, Chimezirim Ezeano, Oluwaseun Oyewo, Ganiyat Adekemi Adeshina
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引用次数: 0

摘要

本文综述了体外受精与儿童神经认知发育关系的研究进展。他们对20项研究进行了分析,其中包括2.3万多名通过体外受精受孕的儿童,并将其与自然受孕的儿童进行了比较。整体认知功能的研究结果是喜忧参半的,以智商来衡量。一些研究表明,试管婴儿和自然受孕的孩子之间没有显著差异,而另一些研究则表明略有差异。尽管还需要更多的研究,但越来越多的证据表明,试管婴儿可能与语言和运动技能等特定的认知领域有关。几个已确定的因素,包括母亲的年龄、教育水平和出生体重,与儿童的认知发展有关,而与受孕方式无关。未来的研究应该探索这些因素如何与体外受精相互作用,并研究更广泛的认知领域。社会经济背景和父母参与是理解儿童发展轨迹的基本考虑因素。一些发现的不确定性突出表明需要进一步研究更大的样本量、更长的随访期和可靠的方法。这项研究对考虑试管婴儿或ICSI的父母、提供指导的医疗保健专业人员以及未来为通过辅助受孕技术受孕的儿童量身定制支持系统具有潜在的意义。关于知识现状的公开交流和负责任的研究成果交流至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A review of the association between in vitro fertilization and children's neurocognitive development.

This review investigated the current research on the association between in vitro fertilization and children's neurocognitive development. Twenty studies were analyzed, encompassing over 23,000 children conceived through IVF, and compared to those conceived naturally. The findings on overall cognitive function were mixed, as measured by IQ. Some studies showed no significant differences between IVF and naturally conceived children, while others suggested slight variations. There is emerging evidence that IVF might correlate with specific cognitive domains like language and motor skills, although more research is needed. Several established factors, including maternal age, education level, and birth weight, are associated with children's cognitive development, regardless of conception method. Future research should explore how these factors interact with IVF and investigate a broader range of cognitive domains. Socioeconomic background and parental involvement are essential considerations for understanding a child's developmental trajectory. The inconclusive nature of some findings highlights the need for further research with larger sample sizes, more extended follow-up periods, and robust methodologies. This research has potential implications for parents considering IVF or ICSI, healthcare professionals providing guidance, and future efforts to tailor support systems for children conceived through assisted conception techniques. Open communication about the current state of knowledge and responsible communication of research findings is crucial.

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来源期刊
CiteScore
5.70
自引率
9.70%
发文量
286
审稿时长
1 months
期刊介绍: The Journal of Assisted Reproduction and Genetics publishes cellular, molecular, genetic, and epigenetic discoveries advancing our understanding of the biology and underlying mechanisms from gametogenesis to offspring health. Special emphasis is placed on the practice and evolution of assisted reproduction technologies (ARTs) with reference to the diagnosis and management of diseases affecting fertility. Our goal is to educate our readership in the translation of basic and clinical discoveries made from human or relevant animal models to the safe and efficacious practice of human ARTs. The scientific rigor and ethical standards embraced by the JARG editorial team ensures a broad international base of expertise guiding the marriage of contemporary clinical research paradigms with basic science discovery. JARG publishes original papers, minireviews, case reports, and opinion pieces often combined into special topic issues that will educate clinicians and scientists with interests in the mechanisms of human development that bear on the treatment of infertility and emerging innovations in human ARTs. The guiding principles of male and female reproductive health impacting pre- and post-conceptional viability and developmental potential are emphasized within the purview of human reproductive health in current and future generations of our species. The journal is published in cooperation with the American Society for Reproductive Medicine, an organization of more than 8,000 physicians, researchers, nurses, technicians and other professionals dedicated to advancing knowledge and expertise in reproductive biology.
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