{"title":"Mixed and undifferentiated autoimmune connective tissue diseases.","authors":"Matthew D Vesely","doi":"10.1016/j.clindermatol.2024.12.011","DOIUrl":null,"url":null,"abstract":"<p><p>Dr. Irwin M. Braverman has advanced our understanding of cutaneous manifestations of autoimmune connective tissue diseases (AI-CTD). Prior to the era of molecular diagnostics, Dr. Braverman's careful clinical observations and detailed descriptions of patients with AI-CTD in his textbook Skin Signs of Systemic Disease provided insights into disease characterization, progression, and evolution. Patients from Dr. Braverman's career who did not fulfill criteria for a single clinical entity, but rather were diagnosed with undifferentiated connective tissue disease or mixed connective tissue disease, are discussed. In addition, key observations of Dr. Braverman into the cutaneous manifestations of Sjögren syndrome and the systemic complications of urticarial vasculitis are highlighted.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clindermatol.2024.12.011","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
Irwin M. Braverman 博士推动了我们对自身免疫性结缔组织疾病（AI-CTD）皮肤表现的认识。在分子诊断时代到来之前，布拉夫曼博士在他的教科书《系统性疾病的皮肤体征》中对自身免疫性结缔组织疾病患者进行了细致的临床观察和详细描述，为疾病的特征描述、进展和演变提供了真知灼见。本文讨论了布拉夫曼医生职业生涯中那些不符合单一临床实体标准，而是被诊断为未分化结缔组织病或混合性结缔组织病的患者。此外，还重点介绍了布拉夫曼博士对斯约恩综合征皮肤表现和荨麻疹性血管炎全身并发症的主要观察结果。
Mixed and undifferentiated autoimmune connective tissue diseases.
Dr. Irwin M. Braverman has advanced our understanding of cutaneous manifestations of autoimmune connective tissue diseases (AI-CTD). Prior to the era of molecular diagnostics, Dr. Braverman's careful clinical observations and detailed descriptions of patients with AI-CTD in his textbook Skin Signs of Systemic Disease provided insights into disease characterization, progression, and evolution. Patients from Dr. Braverman's career who did not fulfill criteria for a single clinical entity, but rather were diagnosed with undifferentiated connective tissue disease or mixed connective tissue disease, are discussed. In addition, key observations of Dr. Braverman into the cutaneous manifestations of Sjögren syndrome and the systemic complications of urticarial vasculitis are highlighted.
期刊介绍：
Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology.
Clinics in Dermatology provides information that is...
• Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice.
• Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise.
• Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.
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