IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY
Gulim Murzakanova, Sari Räisänen, Anne Flem Jacobsen, Branka M Yli, Tiril Tingleff, Katariina Laine
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引用次数: 0

摘要

目的:关于足月选择性引产的益处是否大于其潜在风险的讨论一直在进行。本研究评估了综合临床检查在确定孕龄超过 40-41 周适合进行待产管理的低风险妊娠中的作用,并比较了其结果与早期引产的适应症:方法: 将转诊至一家三级医院的孕周≥ 40 + 0 的孕妇(n = 722)纳入该前瞻性队列。根据初诊决定,将研究对象分为初诊引产组(42 + 0 孕周前引产)和待产管理组(自然临产或 42 + 0 孕周引产)。采用了卡方检验和逻辑回归。结果指标为胎儿综合不良结局(入住新生儿重症监护室、代谢性酸中毒或阿普加评分结果):主要结局指标在初次诱导组(n = 258)和期待管理组(n = 464)之间无显著差异:胎儿综合不良结局(OR = 2.29,95% CI = 0.92-5.68; p = 0.07)、产内剖宫产(OR = 1.00,95% CI = 0.64-1.56;P = 1.00)、产后出血≥ 1500 ml(OR = 1.89,95% CI = 0.92-3.90;P = 0.09)、产褥期产妇发热≥ 38 ℃(OR = 1.26,95% CI = 0.83-1.93;P = 0.28)或产褥期抗生素治疗(OR = 1.25,95% CI = 0.77-2.02;P = 0.37).结论:结论:在妊娠 40-41 周时进行全面的临床检查,可以确定哪些孕妇在妊娠 42 周前可以进行预期管理,从而获得与提前引产相似的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical examination for identifying low-risk pregnancies suitable for expectant management beyond 40-41 gestational weeks: maternal and fetal outcomes.

Purpose: There is an ongoing discussion on whether the benefits of term elective labor induction outweigh its potential risks. This study evaluated the utility of a comprehensive clinical examination in identifying low-risk pregnancies suitable for expectant management beyond gestational age 40‒41 weeks and compared their outcomes with earlier labor induction by indication.

Methods: Pregnant women (n = 722) with ≥ 40 + 0 gestational weeks referred to a tertiary hospital were included in this prospective cohort. The study population was divided into the primary induction group (induction before 42 + 0 gestational weeks) and the expectant management group (spontaneous labor onset or induction at 42 + 0 gestational weeks), by decision based on a primary consultation. The Chi-square test and logistic regression were applied. The outcome measures were composite adverse fetal outcome (admission to a neonatal intensive care unit, metabolic acidosis, or Apgar score < 7 at 5 min), treatment with intrapartum antibiotics, intrapartum maternal fever ≥ 38 °C, intrapartum cesarean section, and postpartum hemorrhage ≥ 1500 ml.

Results: The main outcome measures did not differ significantly between the primary induction group (n = 258) and the expectant management group (n = 464): composite adverse fetal outcome (OR = 2.29, 95% CI = 0.92-5.68; p = 0.07), intrapartum cesarean section (OR = 1.00, 95% CI = 0.64-1.56; p = 1.00), postpartum hemorrhage ≥ 1500 ml (OR = 1.89, 95% CI = 0.92-3.90; p = 0.09), intrapartum maternal fever ≥ 38 °C (OR = 1.26, 95% CI = 0.83-1.93; p = 0.28), or treatment with intrapartum antibiotics (OR = 1.25, 95% CI = 0.77-2.02; p = 0.37).

Conclusion: A comprehensive clinical examination at 40‒41 gestational weeks can identify pregnancies that might be managed expectantly until 42 gestational weeks obtaining similar outcomes to those induced earlier.

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来源期刊
CiteScore
4.70
自引率
15.40%
发文量
493
审稿时长
1 months
期刊介绍: Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report". The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.
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