钯催化炔环己二烯酮和 O-炔基苯磺酰胺的[2 + 2 + 2]环化反应以构建融合三环萘并呋喃

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2024-12-16 DOI:10.1021/acs.joc.4c02447

Miaomiao Tian, Xuxu Ma, Tianyun Zhang, Junbiao Chang, Bingxian Liu

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本文章由计算机程序翻译，如有差异，请以英文原文为准。

Pd-Catalyzed [2 + 2 + 2] Cyclization of Alkyne-cyclohexadienones and O-Akynyl Benzenesulfonamides for Construction of Fused Tricyclic Hydronaphthofurans

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Pd-Catalyzed [2 + 2 + 2] Cyclization of Alkyne-cyclohexadienones and O-Akynyl Benzenesulfonamides for Construction of Fused Tricyclic Hydronaphthofurans

A palladium-catalyzed [2 + 2 + 2] cyclization of 1,6-enynes with unsymmetrical alkynes has been successfully accomplished, resulting in the formation of a series of fused tricyclic hydronaphthofurans with high stereo- and regioselectivity in a single step. This reaction demonstrates 100% atomic economy and exhibits a broad substrate scope.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.