低骨骼肌放射密度预测CDK4/6抑制剂加芳香酶抑制剂对晚期乳腺癌的反应

IF 8.9 1区医学

Journal of Cachexia, Sarcopenia and Muscle Pub Date : 2024-12-17 DOI:10.1002/jcsm.13666

Hyunwook Kim, Seungjin Baek, Sookyeong Han, Gun Min Kim, Joohyuk Sohn, Yumie Rhee, Namki Hong, Min Hwan Kim

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引用次数: 0

摘要

最近的证据表明，宿主代谢失调会影响乳腺癌患者的治疗结果。我们研究了激素受体阳性、her2阴性的晚期乳腺癌（ABC）患者在接受内分泌加CDK4/6抑制剂（CDK4/6i）治疗后，计算机断层扫描（CT）衍生的身体成分指数与治疗反应的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Low Skeletal Muscle Radiodensity Predicts Response to CDK4/6 Inhibitors Plus Aromatase Inhibitors in Advanced Breast Cancer

Recent evidence indicates that a dysregulated host metabolism influences treatment outcomes in patients with breast cancer. We investigated the association of computed tomography (CT)-derived body composition indices with therapeutic responses in patients with hormone receptor-positive, HER2-negative advanced breast cancer (ABC) on endocrine plus CDK4/6 inhibitor (CDK4/6i) treatment.

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来源期刊

Journal of Cachexia, Sarcopenia and Muscle Medicine-Orthopedics and Sports Medicine

自引率

12.40%

发文量

期刊介绍： The Journal of Cachexia, Sarcopenia, and Muscle is a prestigious, peer-reviewed international publication committed to disseminating research and clinical insights pertaining to cachexia, sarcopenia, body composition, and the physiological and pathophysiological alterations occurring throughout the lifespan and in various illnesses across the spectrum of life sciences. This journal serves as a valuable resource for physicians, biochemists, biologists, dieticians, pharmacologists, and students alike.