Laura Saa, Manuel Núñez-Martínez, Eva Carpintero-Cueto and Aitziber L. Cortajarena
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引用次数: 0
摘要
生物分子稳定的金纳米团簇（AuNCs）具有独特的光学特性，同时在生物条件下具有良好的生物相容性和稳定性，因此已成为有趣的功能性纳米材料。在本综述中，我们将探讨利用生物分子配体合成 AuNCs 的主要最新进展。综述了采用氨基酸、肽、蛋白质和 DNA 作为生物分子支架的各种合成方法。此外，还讨论了生物大分子的合成条件和性质对 AuNCs 新出现的光学（吸收和光致发光）和光电性质的影响。最后，介绍了将生物分子稳定的 AuNCs 应用于生物传感、生物成像和治疗学的最新研究成果。
Biomolecular ligands as tools to modulate the optical and chiroptical properties of gold nanoclusters
Biomolecule-stabilized gold nanoclusters (AuNCs) have become functional nanomaterials of interest because of their unique optical properties, together with excellent biocompatibility and stability under biological conditions. In this review, we explore the recent advancements in the application of biomolecular ligands for synthesizing AuNCs. Various synthesis approaches that are employing amino acids, peptides, proteins, and DNA as biomolecular scaffolds are reviewed. Furthermore, the influence of the synthesis conditions and nature of the biomolecule on the emerging optical (absorption and photoluminescence) and chiroptical properties of AuNCs is discussed. Finally, the latest research on the applications of biomolecule-stabilized AuNCs for biosensing, bioimaging, and theranostics is presented.
期刊介绍：
Nanoscale is a high-impact international journal, publishing high-quality research across nanoscience and nanotechnology. Nanoscale publishes a full mix of research articles on experimental and theoretical work, including reviews, communications, and full papers.Highly interdisciplinary, this journal appeals to scientists, researchers and professionals interested in nanoscience and nanotechnology, quantum materials and quantum technology, including the areas of physics, chemistry, biology, medicine, materials, energy/environment, information technology, detection science, healthcare and drug discovery, and electronics.
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