异维A酸病例报告:急性嗜酸性粒细胞肺炎,一种罕见的不良反应。

IF 1 4区 医学 Q4 DERMATOLOGY
Indian Journal of Dermatology Pub Date : 2024-11-01 Epub Date: 2024-10-29 DOI:10.4103/ijd.ijd_75_24
Kadir Küçük
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引用次数: 0

摘要

这是一例急性嗜酸性粒细胞肺炎(AEP)病例,患者 21 岁,患有寻常型痤疮,曾接受异维A酸治疗。在治疗期间,她的血液化验结果显示正常,直到第三个月,嗜酸性粒细胞数量才略有增加。在治疗的第五个月,患者因呼吸急促到肺科门诊就诊。肺部 CT 成像显示双肺浸润,并伴有磨玻璃不透明。根据血液和造影结果,确诊为 AEP。患者终止了异维A酸治疗,开始口服类固醇,症状有所改善。除吸烟外,患者没有其他风险因素,但她在戒烟后没有开始或恢复吸烟。本病例报告强调了异维A酸治疗后发生超敏性肺炎的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report of Isotretinoin: Acute Eosinophilic Pneumonia, A Rare Adverse Reaction.

This is a case of acute eosinophilic pneumonia (AEP) in a 21-year-old woman with acne vulgaris who was treated with isotretinoin. During treatment, her blood tests showed normal results until the third month, when there was a slight increase in eosinophil count. In the fifth month of treatment, the patient presented to the pulmonology outpatient clinic with complaints of shortness of breath. Lung CT imaging revealed infiltration in both lungs characterized by ground glass opacities. AEP was diagnosed based on blood and imaging results. Isotretinoin therapy was terminated, and oral steroids were initiated, resulting in the improvement of the patient's symptoms. The patient had no additional risk factors except for smoking, but she had not started or resumed smoking after quitting. This case report highlights the possibility of hypersensitivity pneumonitis following isotretinoin administration.

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来源期刊
Indian Journal of Dermatology
Indian Journal of Dermatology Medicine-Dermatology
CiteScore
1.80
自引率
0.00%
发文量
217
审稿时长
47 weeks
期刊介绍: The journal publishes information related to skin-pathology and different modes of therapeutics, including dermatosurgery and cosmetic dermatology. Likewise, it carries articles on leprosy, STI and HIV/AIDS. The editorial board encourages the authors to publish articles addressing emerging techniques and developments in the subject specialty, in the form of Original investigations, Narrative and Systematic Reviews as well as Case Reports. The journal aims at publishing Editorials and Commentaries from eminent personalities on a regular basis.
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