{"title":"一种新的多层膜修复技术用于内镜下鼻内肿物切除术中高流量脑脊液泄漏。","authors":"Chuan Shao, Junwei Wang, Pan Wang, Nan Wu","doi":"10.62347/ZIFY3189","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Postoperative cerebrospinal fluid (CSF) leak is a life-threatening complication following endoscopic skull base surgery. This study describes a multilayered membrane reconstruction strategy for treating high-flow intraoperative CSF leaks during expanded endoscopic endonasal tumor resection (EEA) and presents the associated outcomes, supplemented by surgical video documentation.</p><p><strong>Methods: </strong>A retrospective review was performed on patients who underwent multilayered membrane reconstruction for high-flow CSF leaks during EEA.</p><p><strong>Results: </strong>From January 2019 to June 2023, 15 patients undergoing EEA experienced high-flow intraoperative CSF leaks and received multilayered membrane reconstruction. Tumor pathologies included pituitary adenoma, craniopharyngioma, and meningioma. After a median postoperative follow-up of 13 months, no postoperative CSF leakage, intracranial infection, meningitis, and pneumocephalus was detected.</p><p><strong>Conclusion: </strong>Our preliminary experience indicates that the multilayered membrane reconstruction technique may be a reliable method for achieving a watertight closure of high-flow intraoperative CSF leaks during EEA and warrants further study.</p>","PeriodicalId":7731,"journal":{"name":"American journal of translational research","volume":"16 11","pages":"6753-6757"},"PeriodicalIF":1.7000,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645632/pdf/","citationCount":"0","resultStr":"{\"title\":\"A novel multilayered membrane repair technique for high-flow cerebrospinal fluid leaks during expanded endoscopic endonasal tumor resection.\",\"authors\":\"Chuan Shao, Junwei Wang, Pan Wang, Nan Wu\",\"doi\":\"10.62347/ZIFY3189\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Postoperative cerebrospinal fluid (CSF) leak is a life-threatening complication following endoscopic skull base surgery. This study describes a multilayered membrane reconstruction strategy for treating high-flow intraoperative CSF leaks during expanded endoscopic endonasal tumor resection (EEA) and presents the associated outcomes, supplemented by surgical video documentation.</p><p><strong>Methods: </strong>A retrospective review was performed on patients who underwent multilayered membrane reconstruction for high-flow CSF leaks during EEA.</p><p><strong>Results: </strong>From January 2019 to June 2023, 15 patients undergoing EEA experienced high-flow intraoperative CSF leaks and received multilayered membrane reconstruction. Tumor pathologies included pituitary adenoma, craniopharyngioma, and meningioma. After a median postoperative follow-up of 13 months, no postoperative CSF leakage, intracranial infection, meningitis, and pneumocephalus was detected.</p><p><strong>Conclusion: </strong>Our preliminary experience indicates that the multilayered membrane reconstruction technique may be a reliable method for achieving a watertight closure of high-flow intraoperative CSF leaks during EEA and warrants further study.</p>\",\"PeriodicalId\":7731,\"journal\":{\"name\":\"American journal of translational research\",\"volume\":\"16 11\",\"pages\":\"6753-6757\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-11-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645632/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of translational research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.62347/ZIFY3189\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of translational research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.62347/ZIFY3189","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
A novel multilayered membrane repair technique for high-flow cerebrospinal fluid leaks during expanded endoscopic endonasal tumor resection.
Background: Postoperative cerebrospinal fluid (CSF) leak is a life-threatening complication following endoscopic skull base surgery. This study describes a multilayered membrane reconstruction strategy for treating high-flow intraoperative CSF leaks during expanded endoscopic endonasal tumor resection (EEA) and presents the associated outcomes, supplemented by surgical video documentation.
Methods: A retrospective review was performed on patients who underwent multilayered membrane reconstruction for high-flow CSF leaks during EEA.
Results: From January 2019 to June 2023, 15 patients undergoing EEA experienced high-flow intraoperative CSF leaks and received multilayered membrane reconstruction. Tumor pathologies included pituitary adenoma, craniopharyngioma, and meningioma. After a median postoperative follow-up of 13 months, no postoperative CSF leakage, intracranial infection, meningitis, and pneumocephalus was detected.
Conclusion: Our preliminary experience indicates that the multilayered membrane reconstruction technique may be a reliable method for achieving a watertight closure of high-flow intraoperative CSF leaks during EEA and warrants further study.
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