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IF 10.7 1区生物学 Q1 CELL BIOLOGY

Developmental cell Pub Date : 2024-12-16 DOI:10.1016/j.devcel.2024.11.012

Marie-Pierre Junier, Elias A. El-Habr

引用次数: 0

摘要

胶质母细胞瘤细胞表现出显著的可塑性，使它们能够适应环境线索，并通过具有不同特性的各种发育样状态过渡。在本期《发育细胞》（Developmental Cell）杂志上，Loftus 等人发现 ILK 是胶质母细胞瘤细胞在祖细胞样和间质/母细胞样状态之间转换的内在调控因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Emergence of the cell-matrix adhesion element ILK as a player in glioblastoma cell plasticity

Glioblastoma cells exhibit remarkable plasticity, enabling them to adapt to environmental cues and transition through various developmental-like states with distinct properties. In this issue of Developmental Cell, Loftus et al. identify ILK as an intrinsic regulator of glioblastoma cell transitions between progenitor-like and mesenchymal/astrocyte-like states.

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来源期刊

Developmental cell 生物-发育生物学

CiteScore

18.90

自引率

1.70%

发文量

203

审稿时长

3-6 weeks

期刊介绍： Developmental Cell, established in 2001, is a comprehensive journal that explores a wide range of topics in cell and developmental biology. Our publication encompasses work across various disciplines within biology, with a particular emphasis on investigating the intersections between cell biology, developmental biology, and other related fields. Our primary objective is to present research conducted through a cell biological perspective, addressing the essential mechanisms governing cell function, cellular interactions, and responses to the environment. Moreover, we focus on understanding the collective behavior of cells, culminating in the formation of tissues, organs, and whole organisms, while also investigating the consequences of any malfunctions in these intricate processes.