Manon Marechal, Emeline Renard, Patricia Franco, Sofia Da Mota, Noémie Schweitzer, Angelica Tiotiu, Cyril Schweitzer, Laurianne Coutier, Iulia Ioan
{"title":"在真实世界环境中诊断儿童和青少年阻塞性睡眠呼吸暂停综合征的三种简略方法的比较--一项使用多导睡眠图的前瞻性研究。","authors":"Manon Marechal, Emeline Renard, Patricia Franco, Sofia Da Mota, Noémie Schweitzer, Angelica Tiotiu, Cyril Schweitzer, Laurianne Coutier, Iulia Ioan","doi":"10.1007/s00405-024-09143-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Oximetry was proposed as an abbreviated exam, easily accepted by the child, for the diagnosis of obstructive sleep apnea (OSA) for children located in regions where access to pediatric sleep labs is limited. The objective of this study was to determine the diagnostic value of the oxygen desaturation index (ODI), the number of ≥ 3% oxygen desaturations per hour of recording, obtained by portable oximetry performed in parallel with video-polysomnography (PSG), in a cohort of children, with and without comorbidities, referred for OSA.</p><p><strong>Methods: </strong>Data from portable oximetry performed in parallel with PSG were prospectively collected. The diagnostic value, sensitivity, and specificity of ODI to identify a moderate/severe OSA were computed.</p><p><strong>Results: </strong>81 children aged 3 to 18 years were included, 56 (69%) with comorbidities, 50 (62%) with moderate/severe OSA. The area under the ROC curves was 0.92 for ODI by PSG, 0.86 for ODI by PSG's oximetry and 0.78 for ODI by portable oximetry, to diagnose a moderate/severe OSA. All ODIs presented high specificity (1.0 for PSG, 0.90 for PSG's oximetry, 0.87 for portable oximetry) and moderate sensitivity (0.84 for PSG, 0.72 for PSG's oximetry, 0.60 for portable oximetry).</p><p><strong>Conclusion: </strong>In children referred for OSA, particularly in those with a pre-existing comorbidity, ODI obtained by an abbreviated method had high specificity for the diagnosis of moderate/severe OSA and might be used to prioritize the access to a comprehensive sleep recording. Its low sensitivity suggests that a comprehensive sleep exam must be performed in case of a negative test.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison between three abbreviated methods for the diagnosis of obstructive sleep apnea syndrome in children and adolescents in a real-world setting - a prospective study using polysomnography.\",\"authors\":\"Manon Marechal, Emeline Renard, Patricia Franco, Sofia Da Mota, Noémie Schweitzer, Angelica Tiotiu, Cyril Schweitzer, Laurianne Coutier, Iulia Ioan\",\"doi\":\"10.1007/s00405-024-09143-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Oximetry was proposed as an abbreviated exam, easily accepted by the child, for the diagnosis of obstructive sleep apnea (OSA) for children located in regions where access to pediatric sleep labs is limited. The objective of this study was to determine the diagnostic value of the oxygen desaturation index (ODI), the number of ≥ 3% oxygen desaturations per hour of recording, obtained by portable oximetry performed in parallel with video-polysomnography (PSG), in a cohort of children, with and without comorbidities, referred for OSA.</p><p><strong>Methods: </strong>Data from portable oximetry performed in parallel with PSG were prospectively collected. The diagnostic value, sensitivity, and specificity of ODI to identify a moderate/severe OSA were computed.</p><p><strong>Results: </strong>81 children aged 3 to 18 years were included, 56 (69%) with comorbidities, 50 (62%) with moderate/severe OSA. The area under the ROC curves was 0.92 for ODI by PSG, 0.86 for ODI by PSG's oximetry and 0.78 for ODI by portable oximetry, to diagnose a moderate/severe OSA. All ODIs presented high specificity (1.0 for PSG, 0.90 for PSG's oximetry, 0.87 for portable oximetry) and moderate sensitivity (0.84 for PSG, 0.72 for PSG's oximetry, 0.60 for portable oximetry).</p><p><strong>Conclusion: </strong>In children referred for OSA, particularly in those with a pre-existing comorbidity, ODI obtained by an abbreviated method had high specificity for the diagnosis of moderate/severe OSA and might be used to prioritize the access to a comprehensive sleep recording. Its low sensitivity suggests that a comprehensive sleep exam must be performed in case of a negative test.</p>\",\"PeriodicalId\":11952,\"journal\":{\"name\":\"European Archives of Oto-Rhino-Laryngology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-12-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Archives of Oto-Rhino-Laryngology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00405-024-09143-5\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Archives of Oto-Rhino-Laryngology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00405-024-09143-5","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
Comparison between three abbreviated methods for the diagnosis of obstructive sleep apnea syndrome in children and adolescents in a real-world setting - a prospective study using polysomnography.
Background: Oximetry was proposed as an abbreviated exam, easily accepted by the child, for the diagnosis of obstructive sleep apnea (OSA) for children located in regions where access to pediatric sleep labs is limited. The objective of this study was to determine the diagnostic value of the oxygen desaturation index (ODI), the number of ≥ 3% oxygen desaturations per hour of recording, obtained by portable oximetry performed in parallel with video-polysomnography (PSG), in a cohort of children, with and without comorbidities, referred for OSA.
Methods: Data from portable oximetry performed in parallel with PSG were prospectively collected. The diagnostic value, sensitivity, and specificity of ODI to identify a moderate/severe OSA were computed.
Results: 81 children aged 3 to 18 years were included, 56 (69%) with comorbidities, 50 (62%) with moderate/severe OSA. The area under the ROC curves was 0.92 for ODI by PSG, 0.86 for ODI by PSG's oximetry and 0.78 for ODI by portable oximetry, to diagnose a moderate/severe OSA. All ODIs presented high specificity (1.0 for PSG, 0.90 for PSG's oximetry, 0.87 for portable oximetry) and moderate sensitivity (0.84 for PSG, 0.72 for PSG's oximetry, 0.60 for portable oximetry).
Conclusion: In children referred for OSA, particularly in those with a pre-existing comorbidity, ODI obtained by an abbreviated method had high specificity for the diagnosis of moderate/severe OSA and might be used to prioritize the access to a comprehensive sleep recording. Its low sensitivity suggests that a comprehensive sleep exam must be performed in case of a negative test.
期刊介绍:
Official Journal of
European Union of Medical Specialists – ORL Section and Board
Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery
"European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level.
European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.