塔克拉玛干沙漠附近环境空气污染物暴露与代谢综合征之间的关系。

IF 6.2 2区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES
Zhe Wang, Weidong Ji, Yushan Wang, Lin Li, Kai Wang, Hongze Liu, Yining Yang, Yi Zhou
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引用次数: 0

摘要

本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between exposure to ambient air pollutants and metabolic syndrome in the vicinity of the Taklamakan Desert.

Background: Air pollution is a recognized contributor to metabolic syndrome (MetS); but studies in developing regions, including China, remain limited, especially in severely polluted areas near the Taklamakan Desert.

Methods: Health data from 2,689,455 individuals aged ≥ 18 years in five regions near the Taklamakan Desert were analyzed. MetS diagnosed followed the 2016 Chinese Adult Dyslipidaemias Management Guidelines. Spatio-temporal data from satellite observations were employed to estimate ambient pollution levels, encompassing particulate matter with diameters of up to 1.0 µm (PM1), 2.5 µm (PM2.5), and 10 µm (PM10), along with Ozone (O3) and Carbon monoxide (CO). To investigate the association between air pollutants and the prevalence of MetS and its components, Spatial Generalized Linear Mixed Models were applied, with adjustments made for relevant covariates. Additional stratified and sensitivity analyses were conducted to further investigate these relationships.

Results: The study observed a 20.43 % prevalence of MetS. Non-linear analysis indicated a significant association between all pollutants and MetS prevalence. A 10 μg/m³ increase in concentration was associated with the following respective odds ratios: PM1 (1.341, 95 % CI: 1.331, 1.351), PM2.5 (1.036, 95 % CI: 1.034, 1.037), PM10 (1.006, 95 % CI: 1.005, 1.007), O3 (1.385, 95 % CI: 1.374, 1.396), and CO (1.015,95 %, CI: 1.0147, 1.016). The reliability of these associations was supported by further sensitivity analyses, accounting for variations in age, sex, physical activity, and smoking status. Additional analysis indicated links between pollutants and MetS components, including abdominal obesity, glucose metabolism, and lipid profiles.

Conclusions: There is an observed association between long-term exposure to air pollution and a heightened risk of MetS, particularly in men, younger individuals, those who are physically inactive, and smokers.

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来源期刊
CiteScore
12.10
自引率
5.90%
发文量
1234
审稿时长
88 days
期刊介绍: Ecotoxicology and Environmental Safety is a multi-disciplinary journal that focuses on understanding the exposure and effects of environmental contamination on organisms including human health. The scope of the journal covers three main themes. The topics within these themes, indicated below, include (but are not limited to) the following: Ecotoxicology、Environmental Chemistry、Environmental Safety etc.
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