接触微塑料对健康的影响

IF 58.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2024-12-13 DOI:10.1038/s41591-024-03388-7

Karen O’Leary

引用次数: 0

摘要

微塑料和纳米塑料（MNPs）在海洋、空气、土壤和食品供应中无处不在，但有关它们对人体组织和器官影响的证据却大多局限于临床前分析。今年 3 月，一项前瞻性观察研究对 257 名接受手术治疗以疏通动脉的人的颈动脉斑块标本进行了检查，结果在一半以上参与者的颈动脉斑块中发现了 MNPs（特别是聚乙烯和聚氯乙烯）。经过近 3 年的随访，这些 MNP 的存在与心血管事件风险增加 4.5 倍有关。这些发现并不能证明因果关系，但却令人担忧；它们突出表明，迫切需要进一步研究人类接触 MNPs 的主要来源、MNPs 对健康的影响以及这些影响的内在机制：N. Engl.390, 900-910 (2024)

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

期刊介绍： Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.