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IF 1.7 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Open Medicine Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI:10.1515/med-2024-1107

Cong Jin, Lei He, Xi Chen, Jiewen Zheng, Wei He, Weiqi Han

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引用次数: 0

摘要

目的：研究骨质疏松性椎体压缩性骨折（OVCF）患者经皮椎体成形术（PKP）后出现进行性椎体后凸（PK）的相关风险因素：一项单中心回顾性研究（2020年1月至2022年12月）分析了129例接受PKP治疗的OVCF患者。患者被分为PK组和非进行性椎体后凸组。研究人员比较了临床和放射学数据，并通过单变量和多变量回归分析确定了PK的独立风险因素。然后绘制了一个预测PKP术后PK风险因素的提名图：结果：在129名患者中，47人（36.4%）在PKP术后发生了PK。多变量分析确定 PK 的独立风险因素为术前脊柱侧弯角度（OR = 1.26，P = 0.008）、T2 加权成像（T2WI）上的 D 型磁共振成像（MRI）信号变化（OR = 18.49，P = 0.003）、黑线信号（OR = 44.00，P < 0.001）、椎间盘终板复合体（IDEC）损伤（OR = 7.86，P = 0.021）和术后 Oswestry 失能指数（ODI）评分（OR = 1.18，P = 0.004）。基于这些因素的提名图显示出很强的判别能力（曲线下面积 = 0.953）和良好的校准性：结论：术前后凸角度、T2WI 上的 D 型 MRI 信号变化、黑线信号、IDEC 损伤和术后较高的 ODI 评分是 PKP 术后 PK 的独立风险因素。基于这些因素的提名图能准确预测PK风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Risk factors for progressive kyphosis after percutaneous kyphoplasty in osteoporotic vertebral compression fracture.

Purpose: To investigate the risk factors associated with progressive kyphosis (PK) after percutaneous kyphoplasty (PKP) in osteoporotic vertebral compression fractures (OVCFs).

Methods: A single-center retrospective study (January 2020 to December 2022) analyzed 129 OVCF patients treated with PKP. Patients were divided into a PK group and a non-progressive kyphosis group. Clinical and radiological data were compared, and univariate and multivariate regression analyses identified independent risk factors for PK. A nomogram was then developed to predict the risk factors for PK after PKP.

Results: Of 129 patients, 47 (36.4%) experienced PK after PKP. Multivariate analysis identified independent risk factors for PK as preoperative kyphosis angle (OR = 1.26, P = 0.008), Type D magnetic resonance image (MRI) signal change on T2-weighted images (T2WI) (OR = 18.49, P = 0.003), black line signal (OR = 44.00, P < 0.001), intervertebral disc endplate complex (IDEC) injury (OR = 7.86, P = 0.021), and postoperative Oswestry Disability Index (ODI) score (OR = 1.18, P = 0.004). The nomogram, based on these factors, demonstrated strong discriminative performance (area under the curve = 0.953) and good calibration.

Conclusions: Preoperative kyphosis angle, Type D MRI signal change on T2WI, black line signal, IDEC injury, and higher postoperative ODI score are independent risk factors for PK after PKP. A nomogram based on these factors accurately predicts PK risk.

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来源期刊

Open Medicine Medicine-General Medicine

CiteScore

3.00

自引率

0.00%

发文量

153

审稿时长

20 weeks

期刊介绍： Open Medicine is an open access journal that provides users with free, instant, and continued access to all content worldwide. The primary goal of the journal has always been a focus on maintaining the high quality of its published content. Its mission is to facilitate the exchange of ideas between medical science researchers from different countries. Papers connected to all fields of medicine and public health are welcomed. Open Medicine accepts submissions of research articles, reviews, case reports, letters to editor and book reviews.