Diyuan Wei, Qi Wang, Huiping Sui, Yixuan Qin, Han Zhang, Huanxin Meng, Jie Han
{"title":"胶原基质在牙种植体中建立角化粘膜的疗效：一项5年随机对照试验。","authors":"Diyuan Wei, Qi Wang, Huiping Sui, Yixuan Qin, Han Zhang, Huanxin Meng, Jie Han","doi":"10.1111/cid.13422","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To compare the 5-year outcomes of collagen matrix (CM) and free gingival graft (FGG) used to augment the keratinized mucosa (KM) around posterior dental implants.</p>\n </section>\n \n <section>\n \n <h3> Materials and Methods</h3>\n \n <p>Thirty patients (44 implants) with inadequate KM (< 2 mm) on posterior dental implants were randomized into two groups that received KM augmentation with CM or FGG. Clinical measurements comprising the KM width (KMW), buccal mucosal thickness (MT), and clinical parameters were examined in a 5-year follow-up. Marginal bone loss (MBL) was evaluated with standardized radiographs using the paralleling technique. Patient-reported outcomes (PROs) during the first week post-surgery and at the 5-year follow-up were evaluated.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>KMW increased significantly during the follow-up period in both groups. The FGG group had a significantly greater KMW than the CM group at the 1, 2-month follow-up and after the 6-month follow-up. KM shrinkage was observed, and was greatest within the first 2 months post-surgery in both groups. At the 5-year follow-up, the KM shrinkage was significantly different between the groups (FGG: 47%; CM: 70%) (<i>p</i> < 0.01). The MT increased significantly in the FGG group. The clinical parameters and MBL were similar between the groups. The bleeding score in the FGG group was higher than that in the CM group (<i>p</i> < 0.05) within the first 2 days post-surgery, while other PROs scores were similar between groups in the first week post-surgery. At 5-year follow-up, all patients were highly satisfied with the treatments.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>FGG was superior to CM in terms of the KM augmentation and MT increase. Except for a slight difference in self-reported bleeding during the first two post-operative days, CM didn't demonstrate other significant advantages in PROMs.</p>\n </section>\n \n <section>\n \n <h3> Trial Registration</h3>\n \n <p>ChiCTR1800018285 (date of registration: 9/9/2018, retrospectively registered. URL: https://www.chictr.org.cn/showproj.html?proj=24156)</p>\n </section>\n </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 1","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficacy of Collagen Matrix for Establishing Keratinized Mucosa at Dental Implants: A 5-Year Randomized Controlled Trial\",\"authors\":\"Diyuan Wei, Qi Wang, Huiping Sui, Yixuan Qin, Han Zhang, Huanxin Meng, Jie Han\",\"doi\":\"10.1111/cid.13422\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>To compare the 5-year outcomes of collagen matrix (CM) and free gingival graft (FGG) used to augment the keratinized mucosa (KM) around posterior dental implants.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials and Methods</h3>\\n \\n <p>Thirty patients (44 implants) with inadequate KM (< 2 mm) on posterior dental implants were randomized into two groups that received KM augmentation with CM or FGG. Clinical measurements comprising the KM width (KMW), buccal mucosal thickness (MT), and clinical parameters were examined in a 5-year follow-up. Marginal bone loss (MBL) was evaluated with standardized radiographs using the paralleling technique. Patient-reported outcomes (PROs) during the first week post-surgery and at the 5-year follow-up were evaluated.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>KMW increased significantly during the follow-up period in both groups. The FGG group had a significantly greater KMW than the CM group at the 1, 2-month follow-up and after the 6-month follow-up. KM shrinkage was observed, and was greatest within the first 2 months post-surgery in both groups. At the 5-year follow-up, the KM shrinkage was significantly different between the groups (FGG: 47%; CM: 70%) (<i>p</i> < 0.01). The MT increased significantly in the FGG group. The clinical parameters and MBL were similar between the groups. 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Efficacy of Collagen Matrix for Establishing Keratinized Mucosa at Dental Implants: A 5-Year Randomized Controlled Trial
Objectives
To compare the 5-year outcomes of collagen matrix (CM) and free gingival graft (FGG) used to augment the keratinized mucosa (KM) around posterior dental implants.
Materials and Methods
Thirty patients (44 implants) with inadequate KM (< 2 mm) on posterior dental implants were randomized into two groups that received KM augmentation with CM or FGG. Clinical measurements comprising the KM width (KMW), buccal mucosal thickness (MT), and clinical parameters were examined in a 5-year follow-up. Marginal bone loss (MBL) was evaluated with standardized radiographs using the paralleling technique. Patient-reported outcomes (PROs) during the first week post-surgery and at the 5-year follow-up were evaluated.
Results
KMW increased significantly during the follow-up period in both groups. The FGG group had a significantly greater KMW than the CM group at the 1, 2-month follow-up and after the 6-month follow-up. KM shrinkage was observed, and was greatest within the first 2 months post-surgery in both groups. At the 5-year follow-up, the KM shrinkage was significantly different between the groups (FGG: 47%; CM: 70%) (p < 0.01). The MT increased significantly in the FGG group. The clinical parameters and MBL were similar between the groups. The bleeding score in the FGG group was higher than that in the CM group (p < 0.05) within the first 2 days post-surgery, while other PROs scores were similar between groups in the first week post-surgery. At 5-year follow-up, all patients were highly satisfied with the treatments.
Conclusions
FGG was superior to CM in terms of the KM augmentation and MT increase. Except for a slight difference in self-reported bleeding during the first two post-operative days, CM didn't demonstrate other significant advantages in PROMs.
Trial Registration
ChiCTR1800018285 (date of registration: 9/9/2018, retrospectively registered. URL: https://www.chictr.org.cn/showproj.html?proj=24156)
期刊介绍：
The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal.
The range of topics covered by the journals will include but be not limited to:
New scientific developments relating to bone
Implant surfaces and their relationship to the surrounding tissues
Computer aided implant designs
Computer aided prosthetic designs
Immediate implant loading
Immediate implant placement
Materials relating to bone induction and conduction
New surgical methods relating to implant placement
New materials and methods relating to implant restorations
Methods for determining implant stability
A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.
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