石墨烯能量转移的单分子DNA动力学。

IF 36.1 1区生物学 Q1 BIOCHEMICAL RESEARCH METHODS

Nature Methods Pub Date : 2024-12-10 DOI:10.1038/s41592-024-02560-8

Pallav Kosuri

引用次数: 0

摘要

石墨烯能量转移（GET）可用于测量石墨烯表面与荧光染料之间的距离。现在，一种将DNA以受控方向附着在石墨烯上的新策略使得使用GET来跟踪DNA和蛋白质- DNA相互作用的动态与碱基对分辨率成为可能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Single-molecule DNA dynamics with graphene energy transfer

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Single-molecule DNA dynamics with graphene energy transfer

Graphene energy transfer (GET) can be used to measure the distance between a graphene surface and a fluorescent dye. A new strategy for attaching DNA in a controlled orientation onto graphene now makes it possible to use GET to track the dynamics of DNA and protein–DNA interactions with base-pair resolution.

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来源期刊

Nature Methods 生物-生化研究方法

CiteScore

58.70

自引率

1.70%

发文量

326

审稿时长

1 months

期刊介绍： Nature Methods is a monthly journal that focuses on publishing innovative methods and substantial enhancements to fundamental life sciences research techniques. Geared towards a diverse, interdisciplinary readership of researchers in academia and industry engaged in laboratory work, the journal offers new tools for research and emphasizes the immediate practical significance of the featured work. It publishes primary research papers and reviews recent technical and methodological advancements, with a particular interest in primary methods papers relevant to the biological and biomedical sciences. This includes methods rooted in chemistry with practical applications for studying biological problems.