心房颤动患者从华法林到DOAC的结构性转换。

Lakartidningen Pub Date : 2024-12-10
Konrad Nylund, Zainab Al-Hadrawi, Anna Björkenheim
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引用次数: 0

摘要

对于有卒中风险的心房颤动(AF)患者,直接口服抗凝剂(DOAC)已被证明至少与华法林一样有效,具有减少监测要求和降低出血风险等优势。缺点包括严重慢性肾脏疾病患者的数据有限,患者费用较高。2021年中期,瑞典Örebro县地区决定将合适的房颤患者从华法林改为DOAC。在接受华法林治疗的823例患者中,732例被确定为DOAC的合适候选人,其中89%的患者成功转换。从华法林切换到DOAC提供了优势,简化了治疗和监测。然而,在转换之前,必须仔细考虑个人需求和风险因素。由于瑞典的许多患者继续使用华法林,这一举措可能会成为其他地区的典范。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Structured switching from warfarin to DOAC in patients with atrial fibrillation].

In patients with atrial fibrillation (AF) at risk of stroke, direct oral anticoagulants (DOAC) have been shown to be at least as effective as warfarin, offering advantages like reduced monitoring requirements and lower bleeding risks. Disadvantages include limited data in patients with severe chronic kidney disease and higher patient costs. In mid-2021, Region Örebro County, Sweden, decided to switch suitable patients with AF from warfarin to DOAC. Out of the 823 patients receiving warfarin therapy, 732 were identified as suitable candidates for DOAC, and 89 percent of these patients were successfully switched. Switching from warfarin to DOAC offers superiority and simplifies treatment and monitoring. However, individual needs and risk factors must be carefully considered before switching. As many patients in Sweden continue to be prescribed warfarin, this initiative could potentially model for other regions.

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Lakartidningen
Lakartidningen Medicine-Medicine (all)
CiteScore
0.30
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134
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