非肝性高氨血症脑病：晚期胃旁路并发症背景下的尿素循环障碍。

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2024-12-09 eCollection Date: 2024-12-01 DOI:10.14309/crj.0000000000001560

Rached Zeghlache, Tijana Samardzic, Katelyn Norman

{"title":"非肝性高氨血症脑病：晚期胃旁路并发症背景下的尿素循环障碍。","authors":"Rached Zeghlache, Tijana Samardzic, Katelyn Norman","doi":"10.14309/crj.0000000000001560","DOIUrl":null,"url":null,"abstract":"We present the case of a woman with nonhepatic hyperammonemic encephalopathy, a rare complication of bariatric surgery. Proposed mechanism include underlying urea cycle disorders and increased ammonia production. Clinically, states of hyperammonemia present with predominantly neurological symptoms of behavioral disturbances, lethargy, seizures, and coma. Given the high morbidity and mortality rate of nearly 40%, early recognition and treatment of the underlying mechanisms of hyperammonemia are crucial.","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 12","pages":"e01560"},"PeriodicalIF":0.6000,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11630914/pdf/","citationCount":"0","resultStr":"{\"title\":\"Nonhepatic Hyperammonemic Encephalopathy: An Unmasked Urea Cycle Disorder in the Setting of Late Gastric Bypass Complication.\",\"authors\":\"Rached Zeghlache, Tijana Samardzic, Katelyn Norman\",\"doi\":\"10.14309/crj.0000000000001560\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present the case of a woman with nonhepatic hyperammonemic encephalopathy, a rare complication of bariatric surgery. Proposed mechanism include underlying urea cycle disorders and increased ammonia production. Clinically, states of hyperammonemia present with predominantly neurological symptoms of behavioral disturbances, lethargy, seizures, and coma. Given the high morbidity and mortality rate of nearly 40%, early recognition and treatment of the underlying mechanisms of hyperammonemia are crucial.\",\"PeriodicalId\":7394,\"journal\":{\"name\":\"ACG Case Reports Journal\",\"volume\":\"11 12\",\"pages\":\"e01560\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2024-12-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11630914/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACG Case Reports Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14309/crj.0000000000001560\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000001560","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

我们提出的情况下，一名妇女与非肝性高氨血症脑病，一个罕见的并发症的减肥手术。提出的机制包括潜在的尿素循环紊乱和氨产量增加。临床上，高氨血症状态主要表现为行为障碍、嗜睡、癫痫发作和昏迷等神经系统症状。鉴于高氨血症的高发病率和死亡率接近40%，早期识别和治疗高氨血症的潜在机制至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Nonhepatic Hyperammonemic Encephalopathy: An Unmasked Urea Cycle Disorder in the Setting of Late Gastric Bypass Complication.

We present the case of a woman with nonhepatic hyperammonemic encephalopathy, a rare complication of bariatric surgery. Proposed mechanism include underlying urea cycle disorders and increased ammonia production. Clinically, states of hyperammonemia present with predominantly neurological symptoms of behavioral disturbances, lethargy, seizures, and coma. Given the high morbidity and mortality rate of nearly 40%, early recognition and treatment of the underlying mechanisms of hyperammonemia are crucial.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.