{"title":"中性粒细胞胞外陷阱加重海绵状瘤的凝血和神经炎症。","authors":"","doi":"10.1038/s44161-024-00584-z","DOIUrl":null,"url":null,"abstract":"Cerebral cavernous malformations (CCMs) can cause strokes and hemorrhages. A study reveals that blocking the formation of neutrophil extracellular traps (NETs) reduces CCM lesions and the associated clots and neuroinflammation, which suggests that targeting NETs might pave the way for new therapies to manage CCMs.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"3 12","pages":"1385-1386"},"PeriodicalIF":9.4000,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neutrophil extracellular traps worsen clotting and neuroinflammation in cavernomas\",\"authors\":\"\",\"doi\":\"10.1038/s44161-024-00584-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cerebral cavernous malformations (CCMs) can cause strokes and hemorrhages. A study reveals that blocking the formation of neutrophil extracellular traps (NETs) reduces CCM lesions and the associated clots and neuroinflammation, which suggests that targeting NETs might pave the way for new therapies to manage CCMs.\",\"PeriodicalId\":74245,\"journal\":{\"name\":\"Nature cardiovascular research\",\"volume\":\"3 12\",\"pages\":\"1385-1386\"},\"PeriodicalIF\":9.4000,\"publicationDate\":\"2024-12-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature cardiovascular research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44161-024-00584-z\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-024-00584-z","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Neutrophil extracellular traps worsen clotting and neuroinflammation in cavernomas
Cerebral cavernous malformations (CCMs) can cause strokes and hemorrhages. A study reveals that blocking the formation of neutrophil extracellular traps (NETs) reduces CCM lesions and the associated clots and neuroinflammation, which suggests that targeting NETs might pave the way for new therapies to manage CCMs.
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