特应性皮炎和糖尿病——有联系吗?]

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-12-09 DOI:10.1007/s00105-024-05440-6
Adelina-Maria Sendrea, Carmen Maria Salavastru
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摘要

背景:特应性皮炎和糖尿病是慢性、免疫介导的炎症性疾病,显著影响患者的生活质量,也代表了相当大的社会经济负担。尽管近几十年来进行了大量研究,但由于数据稀少,有时甚至相互矛盾,这两种疾病之间的可能联系仍然是一个有争议的话题。然而,它们之间的潜在联系是基于一些公认的共同病理生理特征。目的:总结和评价特应性皮炎与糖尿病的可能关系。材料与方法:对特应性皮炎与糖尿病的相关性进行文献综述。结果:一些研究报道了特应性皮炎与1型或2型糖尿病的相关性。然而,其他研究表明这两种情况之间没有关联,甚至表明特应性皮炎可以降低某些患者患糖尿病的风险。此外,这两种慢性疾病还具有一定的临床特征,提示可能存在相关性。然而,目前还没有明确的科学证据表明特应性皮炎与糖尿病之间存在显著的正相关,这主要是由于缺乏大规模和多样化的人口统计学研究。结论:临床医生应该意识到成人和儿童患者的这种潜在相关性,并考虑跨学科治疗特应性皮炎的重要性。需要进一步的研究来确定特定人群中特应性皮炎和糖尿病之间可能存在的关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Atopic dermatitis and diabetes mellitus-is there a link?]

Background: Atopic dermatitis and diabetes mellitus are chronic, immune-mediated, inflammatory diseases that significantly affect patients' quality of life and also represent a considerable socioeconomic burden. Despite intensive research in recent decades, the possible link between these two medical conditions remains a controversial topic due to sparse and sometimes contradictory data. Nevertheless, the potential link between them is based on some recognized common pathophysiological features.

Aim: To summarize and evaluate a possible association between atopic dermatitis and diabetes mellitus.

Materials and methods: A literature review on the potential association between atopic dermatitis and diabetes mellitus was conducted.

Results: Several studies have reported a correlation between atopic dermatitis and type 1 or type 2 diabetes mellitus. However, other studies have shown no association between these two conditions or even suggested that atopic dermatitis could reduce the risk of developing diabetes mellitus in certain patients. In addition, these two chronic diseases also have certain clinical features that suggest a possible correlation. However, there is currently no clear scientific evidence of a significant positive association between atopic dermatitis and diabetes mellitus, mainly due to the lack of large and diverse demographic studies.

Conclusion: Clinicians should be aware of this potential correlation in both adult and pediatric patients and consider the importance of an interdisciplinary approach for the management of atopic dermatitis. Further research is needed to determine possible associations between atopic dermatitis and diabetes mellitus in specific populations.

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