肥胖与较高数量的甲状腺结节和较差的FNA结果相关。

IF 3.5 2区医学 Q2 ENDOCRINOLOGY & METABOLISM

European Thyroid Journal Pub Date : 2025-01-09 Print Date: 2025-02-01 DOI:10.1530/ETJ-24-0176

Elpida Demetriou, Aliki Economides, Maria Fokou, Demetris Lamnisos, Stavroula A Paschou, Panagiotis Papageorgis, Panayiotis A Economides

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引用次数: 0

摘要

背景：肥胖可能与甲状腺结节有关。然而，其对结节数量和恶性肿瘤风险的影响尚不清楚。目的：利用身体质量指数（BMI）、超声检查（US）和细胞学资料评价肥胖对甲状腺结节的影响。方法：对310例甲状腺结节患者进行回顾性队列研究。根据BMI对患者进行分类，并对灰度美国数据和细针穿刺（FNA）细胞学结果进行评估。结果：BMI≥25 Kg/ m²的患者甲状腺结节数量高于BMI的患者。结论：超重和肥胖患者甲状腺结节数量有增加的趋势，甲状腺恶性肿瘤的诊断风险较高。

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Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes.

Background: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear.

Aim: To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data.

Methods: A retrospective cohort study of 310 patients with thyroid nodules was performed. Patients were categorized based on their BMI, and grayscale US data and fine-needle aspiration cytology results were evaluated.

Results: Patients with BMI ≥ 25 kg/m2 were found to have a higher number of thyroid nodules compared to those with BMI < 25 kg/m2 (4.25 ± 2.42 vs 3.66 ± 1.93) (P value = 0.05). Patients with BMI ≥ 25 kg/m2 had more suspicious and malignant cytology than those with BMI < 25 kg/m2 (P value = 0.029). Patients with BMI ≥ 25 kg/m2 had more nodules with intermediate and high suspicion sonographic patterns. However, this did not reach statistical significance.

Conclusion: Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy.

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来源期刊

European Thyroid Journal Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

6.70

自引率

2.10%

发文量

156

期刊介绍： The ''European Thyroid Journal'' publishes papers reporting original research in basic, translational and clinical thyroidology. Original contributions cover all aspects of the field, from molecular and cellular biology to immunology and biochemistry, from physiology to pathology, and from pediatric to adult thyroid diseases with a special focus on thyroid cancer. Readers also benefit from reviews by noted experts, which highlight especially active areas of current research. The journal will further publish formal guidelines in the field, produced and endorsed by the European Thyroid Association.