基于C-ZIF-67@PAN纳米纤维的电化学感应传感器检测牛奶中氨苄西林。

IF 2.7 3区化学 Q2 CHEMISTRY, ANALYTICAL

Analytical Methods Pub Date : 2024-11-26 DOI:10.1039/D4AY02001D

Yuting Luo, Yiwei Sun, Haoxiang Wang, Yuyang He, Yuxun Zhang, Hailu Lei, Hong Yang, Jinhao Wei and Dongpo Xu

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引用次数: 0

摘要

制备了 C-ZIF-67@PAN 纳米纤维，作为氨苄西林（AMP）检测的活性材料。金属有机框架（MOF）可提供更大的比表面积和更多的结合位点。在进一步碳化过程中，PAN 纤维可以使 ZIF-67 有序排列，增强材料的导电性，使反应更加灵敏。在材料中加入金纳米粒子，并利用 Au-S 键将适配体与材料紧密结合，进一步增强了材料的导电性。在优化条件下，该传感器具有较宽的检测范围（0.001-100 μM）和较低的检测限（0.67 nM）。此外，C-ZIF-67@PAN@Au@Apta 传感器还成功地应用于牛奶样品中的苯丙胺类兴奋剂残留，回收率高达 92.77-101.95%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

An electrochemical aptasensor based on C-ZIF-67@PAN nanofibers for detection of ampicillin in milk

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An electrochemical aptasensor based on C-ZIF-67@PAN nanofibers for detection of ampicillin in milk

C-ZIF-67@PAN nanofibers are prepared as an active material for ampicillin (AMP) detection. Metal organic frameworks (MOFs) can provide larger specific surface area and more binding sites. The PAN fiber in the further carbonization process can make ZIF-67 orderly arranged, enhance the conductivity of the material, and make the response more sensitive. Gold nanoparticles are incorporated into the material, and the aptamer is closely combined with the material by using the Au–S bond to further enhance the conductivity of the material. Under optimized conditions, the sensor has a wide detection range (0.001–100 μM) and a low detection limit (0.67 nM). In addition, the C-ZIF-67@PAN@Au@Apta sensor is successfully applied to AMP residues in milk samples with a recovery rate of 92.77–101.95%.

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