伴有边缘性肾功能的膀胱癌患者肌肉减少症可能增加顺铂的毒性

IF 3.7 2区医学 Q1 UROLOGY & NEPHROLOGY

BJU International Pub Date : 2024-12-09 DOI:10.1111/bju.16606

Eiftu S. Haile, Zaeem Lone, David Shin, Amy S. Nowacki, Nicolas Soputro, Kyle Harris, Rebecca A. Campbell, Andrew Wood, Samuel C. Haywood, Mohamed Eltemamy, Georges-Pascal Haber, Christopher J. Weight, Hadley M. Wood, Jonathan J. Taliercio, Amanda Nizam, Shilpa Gupta, Erick M. Remer, Nima Almassi

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引用次数: 0

摘要

评估肌少症对新辅助化疗（NAC）毒性的影响是否受临界肾功能（估计肾小球滤过率[eGFR] 40-65 mL/min）的影响，以及肌少症和临界肾功能是否与NAC毒性风险独立相关。

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Sarcopenia may increase cisplatin toxicity in bladder cancer patients with borderline renal function

To assess whether the effect of sarcopenia on neoadjuvant chemotherapy (NAC) toxicity is modified by borderline renal function (estimated glomerular filtration rate [eGFR] 40–65 mL/min) and whether sarcopenia and borderline renal function are independently associated with NAC toxicity risk.

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来源期刊

BJU International 医学-泌尿学与肾脏学

CiteScore

9.10

自引率

4.40%

发文量

262

审稿时长

1 months

期刊介绍： BJUI is one of the most highly respected medical journals in the world, with a truly international range of published papers and appeal. Every issue gives invaluable practical information in the form of original articles, reviews, comments, surgical education articles, and translational science articles in the field of urology. BJUI employs topical sections, and is in full colour, making it easier to browse or search for something specific.