步态速度与抑郁症之间的关系——对21世纪高龄成年人的横断面分析。

IF 2.8 3区 医学 Q3 GERIATRICS & GERONTOLOGY
Laura Corneliusson, Jerry Öhlin, Annika Toots, Yngve Gustafson, Birgitta Olofsson
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引用次数: 0

摘要

目的:探讨高龄老年人(≥85岁)步态速度与抑郁症之间的关系。方法:本研究利用gerda数据库,其中包括居住在瑞典北部和芬兰西部的85岁,90岁和95岁以上的代表性样本。从2000年至2017年的四次数据收集中,这项研究包括1794名参与者。测量自定步速超过2.4 m,并由老年医学专家根据DSM-IV-TR标准评估抑郁症。采用t检验和多变量logistic回归来探讨步态速度与抑郁症之间的差异和关联。结果:步态速度与老年人抑郁症独立相关(p < 0.001)。结果显示,有/无抑郁症患者的平均步态速度(m/s)(0.34±0.24/0.52±0.26,p < .001)、有/无抗抑郁药物治疗组的平均步态速度(m/s)(0.35±0.24/0.44±0.24,p < .001)、无抗抑郁药物治疗组的平均步态速度(m/s)(0.36±0.21/0.42±0.22,p = .020)存在显著差异。结论:这是第一项针对高龄成年人的研究,显示了步态速度和抑郁症之间的独立联系。对抗抑郁药物有反应的人比无反应的人有更高的平均步态速度,这可能意味着成功治疗后功能的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The association between gait speed and depressive disorders - A cross-sectional analysis of very old adults in the 21st century.

Objectives: To investigate the association between gait speed and depressive disorders among very old adults (≥85 years).

Method: This study utilized the GERDA-database, which encompasses a representative sample of those aged 85, 90, and 95+ years residing in northern Sweden and western Finland. From four data collections between 2000 and 2017, this study included 1794 participants. Self-paced gait speed was measured over 2.4-m and depressive disorders was evaluated by a specialist in geriatric medicine according to the DSM-IV-TR criteria. T-tests and multivariable logistic regressions were used to explore differences and associations between gait speed and depressive disorders.

Results: Gait speed was independently associated with depressive disorders among very old adults (p < .001). The results showed significantly different mean gait speeds (m/s) between individuals with/without a depressive disorder (0.34 ± 0.24/0.52 ± 0.26, p < .001), between individuals with a depressive disorder with/without antidepressant treatment (0.35 ± 0.24/0.44 ± 0.24, p < .001) and between non-responders/responders to antidepressants (0.36 ± 0.21/0.42 ± 0.22, p = .020).

Conclusion: This is the first study focusing on very old adults that has shown an independent association between gait speed and depressive disorders. Responders to antidepressant medication had a higher mean gait speed than non-responders, which may imply shifts in function upon successful treatment.

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来源期刊
Aging & Mental Health
Aging & Mental Health 医学-精神病学
CiteScore
7.00
自引率
2.90%
发文量
176
审稿时长
4-8 weeks
期刊介绍: Aging & Mental Health provides a leading international forum for the rapidly expanding field which investigates the relationship between the aging process and mental health. The journal addresses the mental changes associated with normal and abnormal or pathological aging, as well as the psychological and psychiatric problems of the aging population. The journal also has a strong commitment to interdisciplinary and innovative approaches that explore new topics and methods. Aging & Mental Health covers the biological, psychological and social aspects of aging as they relate to mental health. In particular it encourages an integrated approach for examining various biopsychosocial processes and etiological factors associated with psychological changes in the elderly. It also emphasizes the various strategies, therapies and services which may be directed at improving the mental health of the elderly and their families. In this way the journal promotes a strong alliance among the theoretical, experimental and applied sciences across a range of issues affecting mental health and aging. The emphasis of the journal is on rigorous quantitative, and qualitative, research and, high quality innovative studies on emerging topics.
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