RENAL Nephrometry Scores and Perioperative Outcomes in Open Partial Nephrectomy.

Objective: To evaluate the efficacy of RENAL nephrometry scores in guiding open partial nephrectomy for renal malignancies and comprehend perioperative factors influencing outcomes.

Study design: Observational study. Place and Duration of the Study: Department of Urology, Pakistan Kidney and Liver Institute and Research Centre, Lahore, Pakistan, from September 2017 to June 2023.

Methodology: The study includes 48 eligible patients undergoing partial nephrectomy for kidney cancer. RENAL scores, preoperative CT scans, patient data, and tumour specifics were collected. Perioperative outcomes, including Clavien-Dindo classification for complications, were recorded. Patient characteristics, tumour details, and continuous variables such as estimated glomerular filtration rate (eGFR) were analysed using IBM SPSS version 20.0.

Results: The study included 48 patients (33 males and 15 females) with a median age of 53 years and a median RENAL score of 8. Clear-cell carcinoma was the dominated histological type (70.83%). The average follow-up duration was 30 months. The RENAL score correlated significantly with ischaemia time, blood loss, tumour size, drainage day, and catheter out day. Postoperative elevation in serum creatinine was associated with male gender and eGFR.

Conclusion: Partial nephrectomy is highly effective for small, locally limited renal tumours, providing favourable outcomes with minimal complications. Tumour size is crucial for reporting, aiding research, and patient counselling. Despite limited correlation with complications, the RENAL nephrometry score remains valuable for defining renal mass characteristics and precise planning in complex localised renal cell carcinoma operations.

Key words: RENAL nephrometry scores, Perioperative outcomes, Open partial nephrectomy, Retrospective analysis, Renal tumours, Renal mass characteristics.