新型第二代聚酯枝晶功能化氧化石墨烯用于高效微固相萃取和尿液中文拉法辛和地文拉法辛的检测。

IF 4 2区化学 Q1 BIOCHEMICAL RESEARCH METHODS

Journal of Chromatography A Pub Date : 2025-01-11 DOI:10.1016/j.chroma.2024.465582

Xuesong Liu , Liuliu Cheng , Yehong Han , Mingyu Wang , Hongyuan Yan

{"title":"新型第二代聚酯枝晶功能化氧化石墨烯用于高效微固相萃取和尿液中文拉法辛和地文拉法辛的检测。","authors":"Xuesong Liu , Liuliu Cheng , Yehong Han , Mingyu Wang , Hongyuan Yan","doi":"10.1016/j.chroma.2024.465582","DOIUrl":null,"url":null,"abstract":"<div><div>A novel adsorbent, second-generation polyester dendritic functionalized graphene oxide (PDG-2), was developed for pipette tip micro solid-phase extraction of venlafaxine and desvenlafaxine from urine. Leveraging the facile modification properties of graphene oxide and the controlled synthesis capabilities of dendritic materials, PDG-2 exhibited a rough surface and numerous active groups with adsorption capacities of desvenlafaxine and venlafaxine up to 187 mg g<sup>−1</sup> and 230 mg g<sup>−1</sup>. Method validation confirmed excellent linearity, low detection limits, high precision, and accurate recovery. Compared with commercial adsorbents, PDG-2 outperformed HLB and MCX and matched the performance of C<sub>18</sub> with a much smaller amount.</div></div>","PeriodicalId":347,"journal":{"name":"Journal of Chromatography A","volume":"1740 ","pages":"Article 465582"},"PeriodicalIF":4.0000,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of a novel second-generation polyester dendritic functionalized graphene oxide for efficient pipette tip micro solid-phase extraction and detection of venlafaxine and desvenlafaxine in urine\",\"authors\":\"Xuesong Liu , Liuliu Cheng , Yehong Han , Mingyu Wang , Hongyuan Yan\",\"doi\":\"10.1016/j.chroma.2024.465582\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A novel adsorbent, second-generation polyester dendritic functionalized graphene oxide (PDG-2), was developed for pipette tip micro solid-phase extraction of venlafaxine and desvenlafaxine from urine. Leveraging the facile modification properties of graphene oxide and the controlled synthesis capabilities of dendritic materials, PDG-2 exhibited a rough surface and numerous active groups with adsorption capacities of desvenlafaxine and venlafaxine up to 187 mg g<sup>−1</sup> and 230 mg g<sup>−1</sup>. Method validation confirmed excellent linearity, low detection limits, high precision, and accurate recovery. Compared with commercial adsorbents, PDG-2 outperformed HLB and MCX and matched the performance of C<sub>18</sub> with a much smaller amount.</div></div>\",\"PeriodicalId\":347,\"journal\":{\"name\":\"Journal of Chromatography A\",\"volume\":\"1740 \",\"pages\":\"Article 465582\"},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2025-01-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Chromatography A\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0021967324009543\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chromatography A","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021967324009543","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}

引用次数: 0

摘要

研究了一种新型吸附剂——第二代聚酯枝晶功能化氧化石墨烯（PDG-2），用于移液头微固相萃取尿液中的文拉法辛和地文拉法辛。利用氧化石墨烯的易改性特性和树突材料的可控合成能力，PDG-2具有粗糙的表面和大量的活性基团，对地文拉法辛和文拉法辛的吸附量分别高达187 mg g-1和230 mg g-1。方法验证线性良好，检出限低，精密度高，回收率准确。与商用吸附剂相比，PDG-2的吸附剂性能优于HLB和MCX，并且与C18的性能相当，但用量少得多。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Development of a novel second-generation polyester dendritic functionalized graphene oxide for efficient pipette tip micro solid-phase extraction and detection of venlafaxine and desvenlafaxine in urine

A novel adsorbent, second-generation polyester dendritic functionalized graphene oxide (PDG-2), was developed for pipette tip micro solid-phase extraction of venlafaxine and desvenlafaxine from urine. Leveraging the facile modification properties of graphene oxide and the controlled synthesis capabilities of dendritic materials, PDG-2 exhibited a rough surface and numerous active groups with adsorption capacities of desvenlafaxine and venlafaxine up to 187 mg g⁻¹ and 230 mg g⁻¹. Method validation confirmed excellent linearity, low detection limits, high precision, and accurate recovery. Compared with commercial adsorbents, PDG-2 outperformed HLB and MCX and matched the performance of C₁₈ with a much smaller amount.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Chromatography A 化学-分析化学

CiteScore

7.90

自引率

14.60%

发文量

742

审稿时长

45 days

期刊介绍： The Journal of Chromatography A provides a forum for the publication of original research and critical reviews on all aspects of fundamental and applied separation science. The scope of the journal includes chromatography and related techniques, electromigration techniques (e.g. electrophoresis, electrochromatography), hyphenated and other multi-dimensional techniques, sample preparation, and detection methods such as mass spectrometry. Contributions consist mainly of research papers dealing with the theory of separation methods, instrumental developments and analytical and preparative applications of general interest.