青少年和年轻成人多发性硬化症患者的妊娠结局：一个病例系列。

IF 5 2区医学 Q1 CLINICAL NEUROLOGY

Multiple Sclerosis Journal Pub Date : 2025-08-01 Epub Date: 2024-12-07 DOI:10.1177/13524585241303490

Gina Chang, Sarah Stoney, Sona Narula

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引用次数: 0

摘要

背景：虽然人们对妊娠对多发性硬化症（MS）临床病程的影响的了解越来越多，但针对年轻人群的研究有限。病例：我们报告了11例26岁前活产的青春期和年轻成年女性儿科发病多发性硬化症患者的14例妊娠的神经系统和产科结果，并描述了其健康的相关社会决定因素。结论：该队列患者的神经系统和产科预后总体良好。在我们的队列中，许多怀孕是计划外的，强调了与所有有生育潜力的MS患者讨论计划生育的重要性。

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Pregnancy outcomes in adolescent and young adult patients with multiple sclerosis: A case series.

Background: While there is increasing understanding of the effect of pregnancy on the clinical course of multiple sclerosis (MS), there are limited studies focused on younger populations.

Cases: We report neurologic and obstetric outcomes for 14 pregnancies from 11 adolescent and young adult female patients with pediatric-onset MS who delivered live births prior to age 26, and describe their relevant social determinants of health.

Conclusion: Neurologic and obstetric outcomes in this cohort were generally good. Many of the pregnancies in our cohort appeared unplanned, underscoring the importance of discussing family planning with all MS patients of childbearing potential.

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来源期刊

Multiple Sclerosis Journal 医学-临床神经学

CiteScore

10.90

自引率

6.90%

发文量

186

审稿时长

3-8 weeks

期刊介绍： Multiple Sclerosis Journal is a peer-reviewed international journal that focuses on all aspects of multiple sclerosis, neuromyelitis optica and other related autoimmune diseases of the central nervous system. The journal for your research in the following areas: * __Biologic basis:__ pathology, myelin biology, pathophysiology of the blood/brain barrier, axo-glial pathobiology, remyelination, virology and microbiome, immunology, proteomics * __Epidemology and genetics:__ genetics epigenetics, epidemiology * __Clinical and Neuroimaging:__ clinical neurology, biomarkers, neuroimaging and clinical outcome measures * __Therapeutics and rehabilitation:__ therapeutics, rehabilitation, psychology, neuroplasticity, neuroprotection, and systematic management Print ISSN: 1352-4585