{"title":"视盘黄斑距离与视盘直径比值在视盘大小定性和定量评价中的作用。","authors":"Akira Ishikawa, Kazumi Kusaka, Akane Nakanishi, Yu Yokoyama","doi":"10.1038/s41433-024-03540-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to evaluate the performance of the optic disc-macula distance to disc-diameter ratio (DM/DD) in qualitative and quantitative assessment of optic disc size.</p><p><strong>Methods: </strong>In 300 apparently normal eyes, we determined the correlation between DM/DD and the planimetric disc area (DA) and evaluated the performance of DM/DD in discriminating between small and large discs. The ability of DM/DD to predict the actual DA was validated in a separate cohort of 200 eyes. The disc size in eyes with glaucoma or related diseases was compared with DA- or DM/DD-based disc size.</p><p><strong>Results: </strong>The DM/DD and its square of inverse (DD<sup>2</sup>/DM<sup>2</sup>) showed excellent non-linear and linear correlations, respectively, with DA (p < 0.001 and p < 0.001, respectively), demonstrating their performance in discriminating between small (<2.04 mm<sup>2</sup>) and large (>2.94 mm<sup>2</sup>) disc sizes with an area under the receiver operating characteristic curve of 0.901 and 0.959, respectively. The difference between the predicted DA and planimetric DA was within ±10% in more than 80% of the eyes. Eyes with suspected and normal-tension glaucoma exhibited larger discs (p < 0.01) when evaluated using both DM/DD and DA. The variation in disc-macula distance seemed to be a confounding factor for DM/DD in inferring the precise disc size.</p><p><strong>Conclusion: </strong>DM/DD, which can be easily calculated from various kinds of fundus photographs or images, was an excellent and interchangeable tool for qualitative and quantitative assessment of disc size, which did not require correction for ocular magnification.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The performance of optic disc-macula distance to disc-diameter ratio in qualitative and quantitative assessment of the optic disc size.\",\"authors\":\"Akira Ishikawa, Kazumi Kusaka, Akane Nakanishi, Yu Yokoyama\",\"doi\":\"10.1038/s41433-024-03540-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>We aimed to evaluate the performance of the optic disc-macula distance to disc-diameter ratio (DM/DD) in qualitative and quantitative assessment of optic disc size.</p><p><strong>Methods: </strong>In 300 apparently normal eyes, we determined the correlation between DM/DD and the planimetric disc area (DA) and evaluated the performance of DM/DD in discriminating between small and large discs. The ability of DM/DD to predict the actual DA was validated in a separate cohort of 200 eyes. The disc size in eyes with glaucoma or related diseases was compared with DA- or DM/DD-based disc size.</p><p><strong>Results: </strong>The DM/DD and its square of inverse (DD<sup>2</sup>/DM<sup>2</sup>) showed excellent non-linear and linear correlations, respectively, with DA (p < 0.001 and p < 0.001, respectively), demonstrating their performance in discriminating between small (<2.04 mm<sup>2</sup>) and large (>2.94 mm<sup>2</sup>) disc sizes with an area under the receiver operating characteristic curve of 0.901 and 0.959, respectively. The difference between the predicted DA and planimetric DA was within ±10% in more than 80% of the eyes. Eyes with suspected and normal-tension glaucoma exhibited larger discs (p < 0.01) when evaluated using both DM/DD and DA. The variation in disc-macula distance seemed to be a confounding factor for DM/DD in inferring the precise disc size.</p><p><strong>Conclusion: </strong>DM/DD, which can be easily calculated from various kinds of fundus photographs or images, was an excellent and interchangeable tool for qualitative and quantitative assessment of disc size, which did not require correction for ocular magnification.</p>\",\"PeriodicalId\":12125,\"journal\":{\"name\":\"Eye\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2024-12-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eye\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41433-024-03540-0\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eye","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41433-024-03540-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
The performance of optic disc-macula distance to disc-diameter ratio in qualitative and quantitative assessment of the optic disc size.
Objectives: We aimed to evaluate the performance of the optic disc-macula distance to disc-diameter ratio (DM/DD) in qualitative and quantitative assessment of optic disc size.
Methods: In 300 apparently normal eyes, we determined the correlation between DM/DD and the planimetric disc area (DA) and evaluated the performance of DM/DD in discriminating between small and large discs. The ability of DM/DD to predict the actual DA was validated in a separate cohort of 200 eyes. The disc size in eyes with glaucoma or related diseases was compared with DA- or DM/DD-based disc size.
Results: The DM/DD and its square of inverse (DD2/DM2) showed excellent non-linear and linear correlations, respectively, with DA (p < 0.001 and p < 0.001, respectively), demonstrating their performance in discriminating between small (<2.04 mm2) and large (>2.94 mm2) disc sizes with an area under the receiver operating characteristic curve of 0.901 and 0.959, respectively. The difference between the predicted DA and planimetric DA was within ±10% in more than 80% of the eyes. Eyes with suspected and normal-tension glaucoma exhibited larger discs (p < 0.01) when evaluated using both DM/DD and DA. The variation in disc-macula distance seemed to be a confounding factor for DM/DD in inferring the precise disc size.
Conclusion: DM/DD, which can be easily calculated from various kinds of fundus photographs or images, was an excellent and interchangeable tool for qualitative and quantitative assessment of disc size, which did not require correction for ocular magnification.
期刊介绍：
Eye seeks to provide the international practising ophthalmologist with high quality articles, of academic rigour, on the latest global clinical and laboratory based research. Its core aim is to advance the science and practice of ophthalmology with the latest clinical- and scientific-based research. Whilst principally aimed at the practising clinician, the journal contains material of interest to a wider readership including optometrists, orthoptists, other health care professionals and research workers in all aspects of the field of visual science worldwide. Eye is the official journal of The Royal College of Ophthalmologists.
Eye encourages the submission of original articles covering all aspects of ophthalmology including: external eye disease; oculo-plastic surgery; orbital and lacrimal disease; ocular surface and corneal disorders; paediatric ophthalmology and strabismus; glaucoma; medical and surgical retina; neuro-ophthalmology; cataract and refractive surgery; ocular oncology; ophthalmic pathology; ophthalmic genetics.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
