白内障手术对玻璃体内治疗视网膜静脉闭塞患者的影响。

IF 4.9 2区 医学 Q1 OPHTHALMOLOGY
Alessandro Invernizzi, Matteo Airaldi, Mariano Cozzi, Vuong Nguyen, Yohei Hashimoto, Daniel Barthelmes, Louise O'Toole, Theodorus Leonardus Ponsioen, Pavol Kusenda, Francisco Javier Lavid, Nandor Jaross, Mark Gillies, Adrian Hunt
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引用次数: 0

摘要

背景:评价玻璃体内注射治疗继发于视网膜静脉阻塞(RVOs)的囊样黄斑水肿(CMO)的白内障手术的临床效果。方法:对行白内障摘除术的RVOs继发性CMO接受玻璃体内注射的眼进行鉴定。注册并按9个参数1:1匹配,同样接受玻璃体内注射的有晶状体对照。比较两组患者术后12个月VA变化、中心亚野厚度(CST)及注射次数。测试了基线特征对最终VA的影响,包括年龄、CST、治疗频率等。结果:我们纳入了193只白内障摘除(暴露)的眼睛和193只未手术的晶状眼(匹配)。暴露眼的VA (95%CI)变化为+9.9(7,12.8)个字母,而匹配眼的VA (95%CI)变化为-2.4(-4.1,-0.7)个字母(p)。结论:白内障摘除治疗继发于RVOs的CMO患者视力良好。与对照组相比,在手术后的12个月内,接受手术的眼睛平均需要更多的注射。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of cataract surgery on patients receiving intravitreal therapy for retinal vein occlusion.

Background: To assess clinical outcomes of cataract surgery in eyes treated with intravitreal injections for cystoid macular oedema (CMO) secondary to retinal vein occlusions (RVOs).

Methods: Eyes receiving intravitreal injections for CMO secondary to RVOs that underwent cataract extraction were identified from the Fight Retinal Blindness! Registry and matched 1:1 by 9 parameters with phakic controls also receiving intravitreal injections for the same condition. VA change at 12 months, central subfield thickness (CST) and injection frequency before and after surgery were compared between the two groups. The effect of baseline features on the final VA including age, CST, treatment frequency among others was tested.

Results: We included 193 eyes that had cataract extraction (exposed) matched with 193 phakic eyes that did not have surgery (matched). VA (95%CI) changed by +9.9 (7, 12.8) letters in exposed eyes versus -2.4 (-4.1, -0.7) letters in matched eyes (p < 0.01). The mean [SD] VA at 12 months was similar in exposed and matched eyes [60.7 (23.0) vs. 61.1 (24.3) letters, respectively, p = 0.81]. The mean [SD] CST was similar between groups before and at surgery, but it was greater in exposed compared with matched eyes [353 (152) vs. 322 (123) μm, respectively, p = 0.03] 12 months after surgery. Exposed eyes received more injections [median (range)] than matched eyes during the 12 months after surgery [5 (3, 7) vs. 4 (1, 6), injections, p < 0.01].

Conclusions: Cataract extraction delivered good visual outcomes in patients treated for CMO secondary to RVOs. More injections were required on average in the 12 months after surgery in eyes undergoing surgery compared to matched controls.

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来源期刊
CiteScore
7.60
自引率
12.50%
发文量
150
审稿时长
4-8 weeks
期刊介绍: Clinical & Experimental Ophthalmology is the official journal of The Royal Australian and New Zealand College of Ophthalmologists. The journal publishes peer-reviewed original research and reviews dealing with all aspects of clinical practice and research which are international in scope and application. CEO recognises the importance of collaborative research and welcomes papers that have a direct influence on ophthalmic practice but are not unique to ophthalmology.
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