运动对抗非小细胞肺癌：新见解。

IF 14.3 1区医学 Q1 ONCOLOGY

Trends in cancer Pub Date : 2025-01-01 Epub Date: 2024-12-04 DOI:10.1016/j.trecan.2024.11.006

Abel Plaza-Florido, Carmen Fiuza-Luces, Alejandro Lucia

引用次数: 0

摘要

运动潜在的“抗癌”效应背后的机制仍然知之甚少。Luo等人最近发现了一种运动诱导的、肌肉来源的细胞外囊泡（EV）相关的miR， miR-29a-3p，在运动对抗非小细胞肺癌（NSCLC）的潜在益处中起着关键作用，包括细胞外基质（ECM）抑制和抗肿瘤免疫反应的改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Exercise against nonsmall-cell lung carcinoma: novel insights.

The mechanisms underlying the potential 'anticancer' effects of exercise remain poorly understood. Luo et al. recently identified an exercise-induced, muscle-derived extracellular vesicle (EV)-associated miR, miR-29a-3p, as a key player in the potential benefits of exercise against nonsmall-cell lung carcinoma (NSCLC), including extracellular matrix (ECM) inhibition and improved antitumoral immune responses.

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来源期刊

Trends in cancer Medicine-Oncology

CiteScore

28.50

自引率

0.50%

发文量

138

期刊介绍： Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.