猪遗传育种新视角:microRNA。

IF 1.6 3区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE
Wei Xiang, Fan Yang, Xiufen Pu, Shuang Zhao, Pingqing Wang
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引用次数: 0

摘要

microRNA (miRNA)是一类在生物体内广泛表达的非编码小RNA分子,在转录后水平对基因表达的调控中起着重要作用。近年来,研究人员开始探索其对家畜发育的影响,并开始思考其在现代分子育种中的潜在作用。越来越多的证据表明,miRNA在猪的生育能力、猪肉产品质量和抗病能力的调控中发挥着核心作用。了解miRNA的生理机制有助于更好地指导今后的育种工作。本文将结合猪的上述经济特性,对miRNA的功能和作用机制的研究进展进行综述。对报道的miRNA及其靶基因进行梳理,评价其在提高猪育肥力、肉质、抗病性等经济性状中的潜在作用,为现代猪分子育种提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A New Perspective on Pig Genetics and Breeding: microRNA.

microRNA (miRNA) is a class of small non-coding RNA molecules that are widely expressed in organisms and play an important role in the regulation of gene expression at the post-transcriptional level. In recent years, researchers have begun to explore its effects on the development of domestic animals and have begun to think about its potential role in modern molecular breeding. Increasing evidence shows that miRNA play a central role in the regulation of pig fertility, pork product quality and disease resistance. Understanding the physiological mechanism of miRNA will be able to better guide future breeding work. In this paper, we will review the research progress of the function and mechanism of miRNA in combination with the above economic characteristics of pigs. The reported miRNA and their target genes were sorted out to evaluate their potential role in improving economic traits such as pig fertility, meat quality and disease resistance, to provide a reference for modern pig molecular breeding.

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来源期刊
Reproduction in Domestic Animals
Reproduction in Domestic Animals 农林科学-奶制品与动物科学
CiteScore
3.00
自引率
5.90%
发文量
238
审稿时长
4-8 weeks
期刊介绍: The journal offers comprehensive information concerning physiology, pathology, and biotechnology of reproduction. Topical results are currently published in original papers, reviews, and short communications with particular attention to investigations on practicable techniques. Carefully selected reports, e. g. on embryo transfer and associated biotechnologies, gene transfer, and spermatology provide a link between basic research and clinical application. The journal applies to breeders, veterinarians, and biologists, and is also of interest in human medicine. Interdisciplinary cooperation is documented in the proceedings of the joint annual meetings. Fields of interest: Animal reproduction and biotechnology with special regard to investigations on applied and clinical research.
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