30%氟化二胺银与非创伤性修复治疗在阻止学龄前儿童牙本质龋齿病变方面的疗效：一项随机临床试验

IF 3.1 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Investigations Pub Date : 2024-12-06 DOI:10.1007/s00784-024-06081-8

Gabriella Fernandes Rodrigues, Ana Lúcia Vollú, Tamiris Ramos Vargas, Luana Mota Kort Kamp, Thuany da Cunha Costa, Lais Rueda Cruz, Ronir Raggio Luiz, Fernanda Barja-Fidalgo, Andréa Fonseca-Gonçalves

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引用次数: 0

摘要

目的：比较氟化二胺银（SDF）与非创伤性修复治疗（ART）治疗龋病的疗效。对治疗时间、不良反应/家长审美、焦虑和患者行为等变量也进行了评估。材料与方法：将初生磨牙合面牙本质龋病患儿（3.53±1.03岁）随机分为实验组（SDF）和对照组（ART）。采用dmf-t和ICDAS指数确定龋的存在。根据活动（活动或不活动）对龋齿病变进行分类。记录进行治疗所需的时间，并通过面部图像量表评估儿童的焦虑程度。不良事件/审美知觉由操作者和护理者记录。弗兰克尔行为量表评估患者的行为。组间比较采用卡方/Fisher精确检验和Mann-Whitney检验。结果：118名接受治疗的参与者中(SDF, n = 59；ART组（n = 59），随访12个月后，SDF组91.5%（43/47）的龋损被抑制，ART组90.2%（46/51）的龋损被抑制（p = 1.000）。24个月后，SDF组有72%（18/25）被捕，ART组有95.2%（20/21）被捕。SDF治疗时间为6.08±1.72次，ART治疗时间为13.58±4.83次(p)。结论：SDF治疗龋损效果与ART相似，但治疗时间更短。两组患者的焦虑、不良反应/审美感知和行为也相似。临床意义：使用SDF可能是一种更快、侵入性更小的治疗龋齿病变的方法。临床试验注册号及注册日期：NCT03063307。2016年9月。

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Efficacy of 30% silver diamine fluoride compared to atraumatic restorative treatment in arresting dentin caries lesions in preschoolers: a randomized clinical trial.

Objective: To compare the efficacy of silver diamine fluoride (SDF) and atraumatic restorative treatment (ART) in arresting caries lesions. Variables such as treatment time, adverse effects/parental aesthetic perception, anxiety and patients' behavior were also evaluated.

Materials and methods: Children (3.53 ± 1.03 years) with dentin caries lesions on the occlusal surface of primary molars were randomized into test (SDF) and control (ART) groups. To determine the presence of caries, dmf-t and ICDAS indexes were used. Caries lesions were also classified according to activity (active or inactive). The time required to perform treatments was recorded and the children's anxiety was assessed by a Facial Image Scale. The adverse events/aesthetic perception were registered by the operator and caregivers. The Frankl Behavioral Scale assessed patients' behavior. The chi-square/Fisher's exact and Mann-Whitney tests were used for comparisons between the groups.

Results: Of the 118 participants who received treatment (SDF, n = 59; ART, n = 59), after 12-month follow-up, 91.5% (43/47) of caries lesions in the SDF and 90.2% (46/51) in the ART group were arrested (p = 1.000). After 24 months, 72% (18/25) were arrested in the SDF group and 95.2% (20/21) in the ART. The treatment times were 6.08 ± 1.72 and 13.58 ± 4.83, for SDF and ART, respectively (p < 0.001). No statistically significant difference of adverse effects, aesthetic perception, anxiety, and patients' behavior were found between the groups.

Conclusions: SDF was similar to ART in arresting caries lesion but required less time for treatment. The anxiety, adverse effects/aesthetic perception and patients' behavior were also similar between the groups. CLINICAL RELEVANCE: The use of SDF may be a faster and less invasive alternative for the treatment of caries lesions. Clinical trial registration number and date of registration: NCT03063307. September 2016.

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来源期刊

Clinical Oral Investigations 医学-牙科与口腔外科

CiteScore

6.30

自引率

5.90%

发文量

484

审稿时长

3 months

期刊介绍： The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.