Kanami Naramoto, Go Kitahara, Sayed Ahmad Nazhat, Masahiro Yasuda, Takeshi Osawa
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Profile of cytokine gene expression of the endometrium and its relationship to inflammation and fertility in postpartum dairy cows.
To clarify the profile of endometrial cytokines and their relation to inflammation and fertility, mRNA expressions of interleukin (IL)-1α, -1β, -8, -10 and tumor necrosis factor (TNF)-α at weeks (W) 3, 5, and 7 postpartum were compared between Holstein cows without and with cytological endometritis and between early (≤90 days) and delayed (>90 days postpartum) conception cows. IL-1α, IL-1β, and IL-8 expressions at W5 and W7 were significantly higher in cows with cytological endometritis than without. While IL-1α, IL-1β, IL-8, and TNF-α expressions decreased from W3 to W5 in all early conception cows, the percentage of cows decreasing these mRNA was significantly lower in delayed conception cows than early conception cows. Evaluating endometrial cytokine expression in dairy cows helps diagnose cytological endometritis and estimate fertility.
期刊介绍：
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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