含3-和4-配位磷的功能化n -酰化氨基酸的合成

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2024-12-06 DOI:10.1007/s11172-024-4417-1

Yu. N. Bubnov, A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, S. V. Baranin

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引用次数: 0

摘要

研究了一种简便的含有3-和4-配位磷基团和n -烷氧羰基的功能化n -酰化氨基酸的合成方法。三配位磷酸酯与n -氯甲基取代的n -烷氧羰基氨基酸的氨基甲基化反应在温和的条件下进行，提供了不同结构的新型靶产物。由此产生的化合物是有前途的生物活性物质，有效的萃取剂和水溶性多齿配体。

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Synthesis of functionalized N-acylated amino acids containing 3- and 4-coordinated phosphorus moieties

A convenient synthesis of functionalized N-acylated amino acids containing 3- and 4-coordinated phosphorus moieties as well as N-alkoxycarbonyl groups has been developed. Aminomethylation of tricoordinated phosphorus acid esters with N-chloromethylsubstituted N-alkoxycarbonylamino acids proceeds under mild conditions and affords new types of target products of different structures. The resulting compounds are of interest as promising biologically active substances, effective extractants, and water-soluble polydentate ligands.

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.