几种咪唑啉受体配体的氚标记

IF 1.5 3区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2024-11-01 DOI:10.1007/s10967-024-09828-5

Crist N. Filer

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引用次数: 0

摘要

生物受体的概念现在已经有一个多世纪的历史了，许多受体家族被确定，因为它们对一系列激动剂和拮抗剂物质的影响作出反应。许多受体已经得到了充分的研究和表征。然而，咪唑啉受体家族是一个更有趣的群体，其生物学问题仍未得到解答。为了更好地了解咪唑啉受体，本工作描述了几种有用的氚标记咪唑啉放射性配体的合成和表征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Tritium labelling of several potent imidazoline receptor ligands

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Tritium labelling of several potent imidazoline receptor ligands

The concept of biological receptors is now more than a century old with numerous receptor families being identified as they respond to the influence of a collection of agonist and antagonist substances. Many receptors have been fully studied and characterized. However, the imidazoline receptor family is one of the more intriguing groups for which unanswered biology questions still remain. To better understand the imidazoline receptors, this work describes the synthesis and characterization of several useful tritium labelled imidazoline radioligands.

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来源期刊

Journal of Radioanalytical and Nuclear Chemistry 化学-分析化学

CiteScore

2.80

自引率

18.80%

发文量

504

审稿时长

2.2 months

期刊介绍： An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.