先天性心脏手术后结缔性异位性心动过速:发病率、危险因素和结果。

Emine Hekim Yılmaz, Nurgül Yurtseven, Oktay Korun, Murat Çiçek, Hüseyin Karadağ, Murat Sürücü, İbrahim Halil Demir, Numan Ali Aydemir, Ahmet Çelebi
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引用次数: 0

摘要

目的:术后交界性异位心动过速(JET)通常是一种自限性疾病;然而,当合并房室分离和术后心室功能障碍时,可能会增加发病率和死亡率。本研究旨在确定先天性心脏手术后JET的总体发病率,确定患者和手术相关的危险因素,并评估JET对预后的临床影响。方法:回顾性分析5年来接受心脏手术的2814例患者的记录,以确定是否存在JET。对于每一个被诊断为JET的患者,选择两个在同一时期接受手术的对照组来比较可能的危险因素和结果。结果:在这个大队列中,先天性心脏手术后JET的发生率为2.66%。单因素分析显示JET与年龄小、体重小、血管活性性肌力评分高、涉及室间隔的手术、手术复杂性评分、体外循环时间增加、胸骨关闭延迟、体外膜氧合(ECMO)要求和术后JET风险增加等因素有统计学意义。在多变量分析中,只有涉及室间隔的手术、ECMO要求和JET风险增加之间存在关联。与对照组相比,JET患者插管时间延长,在重症监护病房和医院停留时间更长,更频繁地进行计划外再干预,死亡率更高。结论:结缔性异位心动过速可导致先天性心脏手术后患者严重的血流动力学后果,并与较差的临床预后相关。患者和手术相关的因素都会增加发生JET的总体风险。确定JET的关联和预测因素有助于改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Junctional Ectopic Tachycardia After Congenital Heart Surgery: Incidence, Risk Factors, and Outcomes.

Objective: Postoperative junctional ectopic tachycardia (JET) is usually a self-limiting condition; however, when combined with atrioventricular dissociation and postoperative ventricular dysfunction, it may increase morbidity and mortality. This study aimed to determine the overall incidence of JET following congenital heart surgery, to identify patient and procedure-related risk factors, and to evaluate the clinical impact of JET on outcomes.

Methods: The records of 2,814 patients who underwent cardiac surgery over a five-year period were reviewed retrospectively to identify those with JET. For each patient diagnosed with JET, two controls who underwent surgery during the same period were selected to compare possible risk factors and outcomes.

Results: The incidence of JET following congenital heart surgery was 2.66% in this large cohort. Univariate analyses revealed statistically significant associations between JET and factors such as young age, small body weight, high vasoactive inotropic score, operations involving the ventricular septum, surgical complexity score, increased cardiopulmonary bypass time, delayed sternal closure, extracorporeal membrane oxygenation (ECMO) requirement, and increased risk of postoperative JET. In multivariate analysis only the association between surgeries involving the ventricular septum, ECMO requirement, and increased risk of JET persisted. Compared to controls, patients with JET experienced prolonged intubation times, longer stays in the intensive care unit and hospital, more frequent unplanned re-interventions, and higher mortality rates.

Conclusion: Junctional ectopic tachycardia can lead to serious hemodynamic consequences in patients following congenital heart surgery and is associated with poorer clinical outcomes. Both patient and procedure-related factors contribute to the overall risk of developing JET. Identifying associations and predictors of JET can help improve patient outcomes.

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