{"title":"[奥卡西平罕见的副作用是肝损伤和多发性浆液炎]。","authors":"Felix Brombacher, Beat Müllhaupt, Abraham Licht","doi":"10.1007/s00108-024-01817-w","DOIUrl":null,"url":null,"abstract":"<p><p>We report the case of a patient with trigeminal neuralgia who developed cholestatic liver injury with systemic inflammation and polyserositis after starting oxcarbazepine therapy. No other causes could be identified. After discontinuation of the drug, there was a complete remission. This case shows that the more modern oxcarbazepine can also cause idiosyncratic liver damage and underlines the importance of high vigilance concerning drug reactions in clinical practice.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"433-435"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Liver injury and polyserositis as rare side effects of oxcarbazepine].\",\"authors\":\"Felix Brombacher, Beat Müllhaupt, Abraham Licht\",\"doi\":\"10.1007/s00108-024-01817-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We report the case of a patient with trigeminal neuralgia who developed cholestatic liver injury with systemic inflammation and polyserositis after starting oxcarbazepine therapy. No other causes could be identified. After discontinuation of the drug, there was a complete remission. This case shows that the more modern oxcarbazepine can also cause idiosyncratic liver damage and underlines the importance of high vigilance concerning drug reactions in clinical practice.</p>\",\"PeriodicalId\":73385,\"journal\":{\"name\":\"Innere Medizin (Heidelberg, Germany)\",\"volume\":\" \",\"pages\":\"433-435\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Innere Medizin (Heidelberg, Germany)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00108-024-01817-w\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Innere Medizin (Heidelberg, Germany)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00108-024-01817-w","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/4 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
[Liver injury and polyserositis as rare side effects of oxcarbazepine].
We report the case of a patient with trigeminal neuralgia who developed cholestatic liver injury with systemic inflammation and polyserositis after starting oxcarbazepine therapy. No other causes could be identified. After discontinuation of the drug, there was a complete remission. This case shows that the more modern oxcarbazepine can also cause idiosyncratic liver damage and underlines the importance of high vigilance concerning drug reactions in clinical practice.