改善社区肺炎病原学诊断的影响。

IF 2.6 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Medicina Clinica Pub Date : 2024-11-30 DOI:10.1016/j.medcli.2024.10.005

Santiago Roques , Pere Tudela , Eduard Clot , Sarah Dávila , Frank Abella , Josep Vega

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引用次数: 0

摘要

背景与目的：社区获得性肺炎（CAP）的病原学诊断仅在30-40%的病例中达到，这往往需要保持经验性抗生素方案。新的呼吸样本核酸扩增技术（NAAT）提高了改善这一临床实践的可能性。我们的目标是分析taan对成本和收益的贡献。患者和方法：对入院的cap进行分析，如果常规诊断测试为阴性，则进行NAAT。如果结果呈阳性，我们评估是否修改了抗菌素、成本估算和隔离措施。结果：共记录64例。病因诊断占65.6%，其中常规诊断占10.9%，TAAN诊断占54.7%。这些试验结果导致88.9%的病例修改了抗菌方案，78.5%的病例进行了隔离。结论：与TAAN的经济成本相比，值得考虑TAAN在减少抗菌药物用量、生态压力和隔离适应症等方面的贡献。

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Impacto de la mejora en el diagnóstico etiológico de la neumonía comunitaria

Background and objective

Etiological diagnosis of community-acquired pneumonia (CAP) is only reached in 30-40% of cases, which frequently requires keeping empirical antibiotic regimens. The new nucleic acid amplification techniques (NAAT) in respiratory samples raise the possibility of improving this clinical practice. Our objective was to analyze TAANs contribution estimating both their costs and benefits.

Patients and methods

The admitted CAPs were analyzed, in which, if the conventional diagnostic tests were negative, a NAAT was performed. If positive results was made, we assessed if antimicrobials were modified, a cost estimate, and isolation measures.

Results

64 cases were documented. An etiological diagnosis was made in 65.6%: 10.9% were obtained by conventional techniques and the rest (54.7%) by TAAN. These tests’ results led to antimicrobial regimen's modification in 88.9% of cases and isolations in 78.5%

Conclusions

Compared to TAAN's economic cost, it is worth considering its contributions, such as antimicrobials’ reduction, ecological pressure, and isolations’ indications

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来源期刊

Medicina Clinica 医学-医学：内科

CiteScore

3.10

自引率

5.10%

发文量

295

审稿时长

22 days

期刊介绍： Medicina Clínica, fundada en 1943, es una publicación quincenal dedicada a la promoción de la investigación y de la práctica clínica entre los especialistas de la medicina interna, así como otras especialidades. Son características fundamentales de esta publicación el rigor científico y metodológico de sus artículos, la actualidad de los temas y, sobre todo, su sentido práctico, buscando siempre que la información sea de la mayor utilidad en la práctica clínica.