骨质疏松性椎体压缩性骨折经皮后凸成形术后邻近椎间盘退变的危险因素分析。

IF 2.5 3区 医学 Q2 CLINICAL NEUROLOGY
Journal of Pain Research Pub Date : 2024-11-25 eCollection Date: 2024-01-01 DOI:10.2147/JPR.S486668
He Song, Aobo Wang, Lei Zang, Tianyi Wang, Shuo Yuan, Ning Fan, Peng Du
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引用次数: 0

摘要

目的:邻近椎间盘退变(ADD)是经皮后凸成形术(PKP)术后常见的并发症。然而,PKP后ADD的危险因素尚未见报道。本研究旨在确定PKP后骨质疏松性椎体压缩性骨折(OVCF)是否与ADD的高风险相关,并确定ADD的危险因素。患者和方法:回顾性分析2015年1月至2021年1月在我们中心连续接受PKP的患者。计算ADD的发病率,并确定ADD的特定亚组。使用单变量和多变量分析对人口统计学、临床基线和放射学数据进行分析,以确定与ADD相关的危险因素。结果:纳入130例符合条件的患者,与原发性变性不同的ADD发病率为42.3%。接受PKP的ovcf患者发展为ADD的风险很高。独立危险因素包括存在椎间盘内水泥渗漏(ICL;优势比[OR] 6.292;95%置信区间[CI] 2.588-15.299;P < 0.001)和术前损伤椎体的颅椎间盘退变(Pfirrmann分级≥IV;或3.575;95% ci 1.515-8.438;P = 0.004)。结论:OVCFs患者行PKP后更易发生ADD,且椎间盘退变多发生在损伤水平以上椎体。ICL和术前损伤椎体退变(Pfirrmann分级≥IV级)是这些患者发生ADD的独立危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of Risk Factors Causing Adjacent Disc Degeneration After Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fractures.

Purpose: Adjacent disc degeneration (ADD) is a common postoperative complication after percutaneous kyphoplasty (PKP). However, risk factors for ADD after PKP have not been reported. This study aimed to determine whether osteoporotic vertebral compression fracture (OVCF) following PKP is associated with a high risk for ADD and to identify the risk factors for ADD.

Patients and methods: Consecutive patients who underwent PKP at our center between January 2015 and January 2021 were retrospectively reviewed. The incidence of ADD was calculated and specific subgroups of ADD were identified. Demographic, clinical baseline, and radiologic data were analyzed using univariate and multivariate analyses to identify the risk factors associated with ADD.

Results: 130 eligible patients were included, and the incidence rate of ADD distinct from primary degeneration was 42.3%. Patients with OVCFs who underwent PKP had a high risk of developing ADD. The independent risk factors included the presence of intradiscal cement leakage (ICL; odds ratio [OR] 6.292; 95% confidence interval [CI] 2.588-15.299; P < 0.001) and pre-operative cranial disc of the injured vertebrae degeneration (Pfirrmann grade ≥IV; OR 3.575; 95% CI 1.515-8.438; P = 0.004).

Conclusion: Patients with OVCFs who underwent PKP were more likely to develop ADD, and most of the degenerated discs occurred in the vertebrae above the level of injury. ICL and pre-operative cranial disc of the injured vertebrae degeneration (Pfirrmann grade ≥IV) were independent risk factors for developing ADD in these patients.

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来源期刊
Journal of Pain Research
Journal of Pain Research CLINICAL NEUROLOGY-
CiteScore
4.50
自引率
3.70%
发文量
411
审稿时长
16 weeks
期刊介绍: Journal of Pain Research is an international, peer-reviewed, open access journal that welcomes laboratory and clinical findings in the fields of pain research and the prevention and management of pain. Original research, reviews, symposium reports, hypothesis formation and commentaries are all considered for publication. Additionally, the journal now welcomes the submission of pain-policy-related editorials and commentaries, particularly in regard to ethical, regulatory, forensic, and other legal issues in pain medicine, and to the education of pain practitioners and researchers.
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