PSMA在下肢淋巴水肿和鞘膜积液中的积累。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-12-03 DOI:10.1097/RLU.0000000000005613

Merve Nida Calderon Tobar, Lutfi Perktas, Hasan Önner

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引用次数: 0

摘要

摘要：放射标记的小分子前列腺特异性膜抗原（PSMA）抑制剂的开发促进了前列腺癌的分子显像。使用177Lu-PSMA尤其有益，因为它的治疗性β发射与γ辐射相结合，可以对前列腺癌患者进行精确治疗和全面成像。我们提出一个病例的前列腺癌患者谁发展下肢淋巴水肿和积液继发于先前的放疗。177Lu-PSMA治疗后的全身成像显示真皮回流，下肢软组织明显积聚和鞘膜积液。

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PSMA Accumulation in Lower Extremity Lymphedema and Hydrocele.

Abstract: The development of radiolabeled small-molecule prostate-specific membrane antigen (PSMA) inhibitors has advanced molecular imaging in prostate cancer. The use of 177 Lu-PSMA is especially beneficial because its therapeutic β-emission combined with γ-radiation enables precise treatment and comprehensive imaging in patients with prostate cancer. We present a case of a prostate cancer patient who developed lower extremity lymphedema and hydrocele secondary to prior radiotherapy. Posttherapy whole-body imaging following 177 Lu-PSMA treatment revealed dermal backflow with a notable accumulation of soft tissue in the lower extremities and hydrocele.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.